A lysosome specific ratiometric fluorescent probe for detection of bisulfite ion based on hybrid coumarin-benzimidazolium compounds

doi:10.1080/10426507.2020.1835904

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	A lysosome specific ratiometric fluorescent probe for detection of bisulfite ion based on hybrid coumarin-benzimidazolium compounds
	Zhao, JD ; Huang, LL ; Yan, ML ; Qu, Y ; Feng, HD ; Sun, YH
刊名	PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
	2020
卷号	196 期号:3 页码:321-327
关键词	SO2 DERIVATIVES BISULFITE SELECTIVE DETECTION RAPID DETECTION POLARITY CYANIDE FRET CHEMOSENSOR
ISSN号	1042-6507
DOI	10.1080/10426507.2020.1835904
文献子类	期刊论文
英文摘要	Hybrid 2-(2-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)vinyl)-1,3-dimethyl-1H-benzo[d]imidazol-3-ium iodide compounds (LHZD-1 similar to 3) were synthesized by Knoevenagel condensation reaction. Their structures were confirmed by H-1 NMR, C-13 NMR and HRMS spectroscopy. The fluorescence property of LHZD-1 similar to 3 varied with the substituent groups such as -Br, -H and -OMe in the benzimidazolium skeleton. The probe LHZD-1 showed remarkable selectivity for the bisulfite ion over other common anions and biotins, which outputted the obvious color change in both absorption (462 nm to 400 nm) and emission (580 nm to 480 nm) spectra. The probe LHZD-1 showed the lysosome positioning action in Hela cells. This study not only provides a way for optimizing coumarin-benzimidazolium probes but also holds considerable promise in detection of bisulfite ion in organelles.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/32680]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China 2.Shanghai Univ Engn Sci, Coll Chem & Chem Engn, 333 Longteng Rd, Shanghai 201620, Peoples R China 3.Univ Chinese Acad Sci, Lab Phys Biol, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zhao, JD,Huang, LL,Yan, ML,et al. A lysosome specific ratiometric fluorescent probe for detection of bisulfite ion based on hybrid coumarin-benzimidazolium compounds[J]. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS,2020,196(3):321-327.
APA	Zhao, JD,Huang, LL,Yan, ML,Qu, Y,Feng, HD,&Sun, YH.(2020).A lysosome specific ratiometric fluorescent probe for detection of bisulfite ion based on hybrid coumarin-benzimidazolium compounds.PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS,196(3),321-327.
MLA	Zhao, JD,et al."A lysosome specific ratiometric fluorescent probe for detection of bisulfite ion based on hybrid coumarin-benzimidazolium compounds".PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 196.3(2020):321-327.