Metal coordination induced SERS nanoprobe for sensitive and selective detection of histamine in serum

doi:10.1016/j.talanta.2021.122913

	Metal coordination induced SERS nanoprobe for sensitive and selective detection of histamine in serum
	Li, Pan 1; Zhou, Binbin 4; Ge, Meihong 1; Jing, Xianghong 3; Yang, Liangbao 1,2
刊名	TALANTA
	2022-01-15
卷号	237
关键词	SERS Metal coordination SERS nanoprobe Neurotransmitter Histamine
ISSN号	0039-9140
DOI	10.1016/j.talanta.2021.122913
通讯作者	Jing, Xianghong(jingxh@mail.cintcm.ac.cn) ; Yang, Liangbao(lbyang@iim.ac.cn)
英文摘要	Sensitivity and credibility detecting histamine (HA) as an important neurotransmitter in biofluids is of importance in analytical science and physiology. Surface-enhanced Raman spectroscopy (SERS) is able to realize the high sensitivity with single molecules level, but providing the high sensitivity for HA with a small cross section remains a challenge. Here we develop the metal complex-based SERS nanoprobe nitrilotriacetic acid-Ni2+ (NTA-Ni2+) combined with self-assemble Au NPs active substrates for sensitive detection of HA. The NTA-Ni2+ can capture the HA molecules close to Au NPs substrates and then amplify the Raman signals of HA owing to the formation of a complex of NTA-Ni2+-HA. The self-assemble Au film through the evaporation-driven method can provide the high-density hot spots substrate with high stability and reproducibility. The NTA-Ni2+ decorated Au NPs as nanoprobe responds to HA with 1 mu M level of sensitivity. More importantly, the developed SERS nanoprobe composing of NTA-Ni2+ and self-assemble Au NPs can be utilized to detect and monitor the HA spiked into serum, indicating the potential prospect in analysis of HA in complex specimen.
资助项目	Nature Science Research Project of Anhui Province[1908085QB65] ; National Science Foundation of China[21974142]
WOS关键词	ENHANCED RAMAN-SPECTROSCOPY ; BLOOD-PLASMA ; SURFACE ; RESONANCE ; SCATTERING ; FISH ; SUBSTRATE ; ARRAYS
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000705224700005
资助机构	Nature Science Research Project of Anhui Province ; National Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/125493]
专题	中国科学院合肥物质科学研究院
通讯作者	Jing, Xianghong; Yang, Liangbao
作者单位	1.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Hlth & Med Technol, Hefei 230031, Anhui, Peoples R China 2.Hefei Canc Hosp, Chinese Acad Sci, Dept Pharm, Hefei 230031, Anhui, Peoples R China 3.China Acad Chinese Med, Inst Acupuncture & Moxibust, Beijing 100700, Peoples R China 4.City Univ Hong Kong, Dept Mech Engn, Kowloon, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Li, Pan,Zhou, Binbin,Ge, Meihong,et al. Metal coordination induced SERS nanoprobe for sensitive and selective detection of histamine in serum[J]. TALANTA,2022,237.
APA	Li, Pan,Zhou, Binbin,Ge, Meihong,Jing, Xianghong,&Yang, Liangbao.(2022).Metal coordination induced SERS nanoprobe for sensitive and selective detection of histamine in serum.TALANTA,237.
MLA	Li, Pan,et al."Metal coordination induced SERS nanoprobe for sensitive and selective detection of histamine in serum".TALANTA 237(2022).