Ubiquitin-specific peptidase 22 in cancer | |
Feng, Tingting1,2,3,4; Ling, Sunbin1; Xu, Chenyang2; Ying, Lisha3; Su, Dan2; Xu, Xiao1 | |
刊名 | CANCER LETTERS |
2021-08-28 | |
卷号 | 514 |
关键词 | Deubiquitination Neoplasms Cell cycle regulation Stemness maintenance Immune microenvironment |
ISSN号 | 0304-3835 |
DOI | 10.1016/j.canlet.2021.05.004 |
通讯作者 | Su, Dan(sudan@zjcc.org.cn) ; Xu, Xiao(zjxu@zju.edu.cn) |
英文摘要 | Recently, many studies have shown that deubiquitination modification of proteins is of great significance in major physiological processes such as cell proliferation, apoptosis, and differentiation. The ubiquitin-specific peptidase (USP) family is one of the most numerous and structurally diverse of the deubiquitinates known to date. USP22, an important member of the USP family, has been found to be closely associated with tumor cell cycle regulation, stemness maintenance, invasion and metastasis, chemoresistance, and immune regulation. We focus on recent advances regarding USP22's function in cancer and discuss the prospect of USP22 in this review. |
资助项目 | National Natural Science Funds for Distinguished Young Scholar of China[81625003] ; Medical Health Science and Technology Project of Zhejiang Province Grant[2019RC130] ; Public WelfareTechnology Foundation of Zhejiang Province of China Grant[2017C34001] ; National Natural Science Foundation of China[81902407] |
WOS关键词 | EPITHELIAL-MESENCHYMAL TRANSITION ; CARCINOMA-CELL-PROLIFERATION ; CLASS SWITCH RECOMBINATION ; USP22 PROMOTES ; HISTONE H2B ; HEPATOCELLULAR-CARCINOMA ; TRANSCRIPTIONAL ACTIVATION ; STRUCTURAL BASIS ; POOR-PROGNOSIS ; DEUBIQUITINATION |
WOS研究方向 | Oncology |
语种 | 英语 |
出版者 | ELSEVIER IRELAND LTD |
WOS记录号 | WOS:000659870600003 |
资助机构 | National Natural Science Funds for Distinguished Young Scholar of China ; Medical Health Science and Technology Project of Zhejiang Province Grant ; Public WelfareTechnology Foundation of Zhejiang Province of China Grant ; National Natural Science Foundation of China |
内容类型 | 期刊论文 |
源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/123811] |
专题 | 中国科学院合肥物质科学研究院 |
通讯作者 | Su, Dan; Xu, Xiao |
作者单位 | 1.Zhejiang Univ, Affiliated Hangzhou Peoples Hosp 1, Ctr Integrated Oncol & Precis Med, Sch Med,Dept Hepatobiliary & Pancreat Surg, Hangzhou 310006, Peoples R China 2.Chinese Acad Sci, Univ Chinese Acad Sci, Zhejiang Canc Hosp, Inst Basic Med & Canc IBMC,Dept Pathol,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China 3.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Basic Med & Canc IBMC, Zhejiang Canc Hosp,Canc Res Inst,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China 4.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Basic Med & Canc IBMC, Zhejiang Canc Hosp,Dept Colorectal Med,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China |
推荐引用方式 GB/T 7714 | Feng, Tingting,Ling, Sunbin,Xu, Chenyang,et al. Ubiquitin-specific peptidase 22 in cancer[J]. CANCER LETTERS,2021,514. |
APA | Feng, Tingting,Ling, Sunbin,Xu, Chenyang,Ying, Lisha,Su, Dan,&Xu, Xiao.(2021).Ubiquitin-specific peptidase 22 in cancer.CANCER LETTERS,514. |
MLA | Feng, Tingting,et al."Ubiquitin-specific peptidase 22 in cancer".CANCER LETTERS 514(2021). |
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