Ubiquitin-specific peptidase 22 in cancer
Feng, Tingting1,2,3,4; Ling, Sunbin1; Xu, Chenyang2; Ying, Lisha3; Su, Dan2; Xu, Xiao1
刊名CANCER LETTERS
2021-08-28
卷号514
关键词Deubiquitination Neoplasms Cell cycle regulation Stemness maintenance Immune microenvironment
ISSN号0304-3835
DOI10.1016/j.canlet.2021.05.004
通讯作者Su, Dan(sudan@zjcc.org.cn) ; Xu, Xiao(zjxu@zju.edu.cn)
英文摘要Recently, many studies have shown that deubiquitination modification of proteins is of great significance in major physiological processes such as cell proliferation, apoptosis, and differentiation. The ubiquitin-specific peptidase (USP) family is one of the most numerous and structurally diverse of the deubiquitinates known to date. USP22, an important member of the USP family, has been found to be closely associated with tumor cell cycle regulation, stemness maintenance, invasion and metastasis, chemoresistance, and immune regulation. We focus on recent advances regarding USP22's function in cancer and discuss the prospect of USP22 in this review.
资助项目National Natural Science Funds for Distinguished Young Scholar of China[81625003] ; Medical Health Science and Technology Project of Zhejiang Province Grant[2019RC130] ; Public WelfareTechnology Foundation of Zhejiang Province of China Grant[2017C34001] ; National Natural Science Foundation of China[81902407]
WOS关键词EPITHELIAL-MESENCHYMAL TRANSITION ; CARCINOMA-CELL-PROLIFERATION ; CLASS SWITCH RECOMBINATION ; USP22 PROMOTES ; HISTONE H2B ; HEPATOCELLULAR-CARCINOMA ; TRANSCRIPTIONAL ACTIVATION ; STRUCTURAL BASIS ; POOR-PROGNOSIS ; DEUBIQUITINATION
WOS研究方向Oncology
语种英语
出版者ELSEVIER IRELAND LTD
WOS记录号WOS:000659870600003
资助机构National Natural Science Funds for Distinguished Young Scholar of China ; Medical Health Science and Technology Project of Zhejiang Province Grant ; Public WelfareTechnology Foundation of Zhejiang Province of China Grant ; National Natural Science Foundation of China
内容类型期刊论文
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/123811]  
专题中国科学院合肥物质科学研究院
通讯作者Su, Dan; Xu, Xiao
作者单位1.Zhejiang Univ, Affiliated Hangzhou Peoples Hosp 1, Ctr Integrated Oncol & Precis Med, Sch Med,Dept Hepatobiliary & Pancreat Surg, Hangzhou 310006, Peoples R China
2.Chinese Acad Sci, Univ Chinese Acad Sci, Zhejiang Canc Hosp, Inst Basic Med & Canc IBMC,Dept Pathol,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China
3.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Basic Med & Canc IBMC, Zhejiang Canc Hosp,Canc Res Inst,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China
4.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Basic Med & Canc IBMC, Zhejiang Canc Hosp,Dept Colorectal Med,Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China
推荐引用方式
GB/T 7714
Feng, Tingting,Ling, Sunbin,Xu, Chenyang,et al. Ubiquitin-specific peptidase 22 in cancer[J]. CANCER LETTERS,2021,514.
APA Feng, Tingting,Ling, Sunbin,Xu, Chenyang,Ying, Lisha,Su, Dan,&Xu, Xiao.(2021).Ubiquitin-specific peptidase 22 in cancer.CANCER LETTERS,514.
MLA Feng, Tingting,et al."Ubiquitin-specific peptidase 22 in cancer".CANCER LETTERS 514(2021).
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