Stimuli-activatable nanomaterials for phototherapy of cancer

doi:10.1088/1748-605X/abfa6e

	Stimuli-activatable nanomaterials for phototherapy of cancer
	Zhou, Mengjiao 1; Liu, Xiao 1,2,3; Chen, Fangmin 2,3; Yang, Lili 1; Yuan, Minjian 1; Fu, Ding-Yi 1; Wang, Weiqi 1,2,3; Yu, Haijun 2,3,4
刊名	BIOMEDICAL MATERIALS
	2021-07-01
卷号	16 期号:4 页码:11
关键词	cancer treatment photodynamic therapy photothermal therapy intelligent nanomaterials stimuli-responsiveness
ISSN号	1748-6041
DOI	10.1088/1748-605X/abfa6e
通讯作者	Wang, Weiqi(wwq1990@ntu.edu.cn) ; Yu, Haijun(hjyu@simm.ac.cn)
英文摘要	Phototherapy including photothermal therapy (PTT) and photodynamic therapy (PDT), as non-invasive therapy approaches, have gained accumulated attention for cancer treatment in past years. PTT and PDT can generate local hyperthermia effects and reactive oxygen species (ROS) respectively, for tumor eradication. To improve the therapeutic performance while minimizing the reverse side effects of phototherapy, extensive efforts have been devoted to developing stimuli-activatable (e.g. pH, redox, ROS, enzyme, etc) nanomaterials for tumor-specific delivery/activation of the phototherapeutics. In this review, we first overviewed the recent advances of the engineered stimuli-responsive nanovectors for the phototherapy of cancer. We particularly summarized the progress of stimuli-activatable nanomaterials-based combinatory therapy strategies for augmenting the performance of phototherapy. We further discuss challenges for the clinical translation of nanomaterials-based phototherapy.
资助项目	National Natural Science Foundation of China[31900990] ; Youth Natural Science Fund of Jiangsu Province[BK20200977] ; Youth Natural Science Fund of Jiangsu Province[BK20200972] ; Nantong Municipal Science and Technology Project[JC2019103] ; Jiangsu College Students'Innovation and Entrepreneurship Training Program[202010304124Y] ; Jiangsu College Students'Innovation and Entrepreneurship Training Program[201910304124Y] ; Basic Research Program of Shenzhen, Science and Technology Development Fund[JCYJ20180227175420974]
WOS关键词	METAL-ORGANIC FRAMEWORKS ; PHOTODYNAMIC THERAPY ; INORGANIC NANOMATERIALS ; NANOPARTICLES ; TUMORS ; ROS
WOS研究方向	Engineering ; Materials Science
语种	英语
出版者	IOP PUBLISHING LTD
WOS记录号	WOS:000649642000001
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/296670]
专题	中国科学院上海药物研究所
通讯作者	Wang, Weiqi; Yu, Haijun
作者单位	1.Nantong Univ, Sch Pharm, Dept Pharmacol, Nantong 226000, Jiangsu, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China 4.Peking Univ, Shenzhen Inst, Shenzhen 518055, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Mengjiao,Liu, Xiao,Chen, Fangmin,et al. Stimuli-activatable nanomaterials for phototherapy of cancer[J]. BIOMEDICAL MATERIALS,2021,16(4):11.
APA	Zhou, Mengjiao.,Liu, Xiao.,Chen, Fangmin.,Yang, Lili.,Yuan, Minjian.,...&Yu, Haijun.(2021).Stimuli-activatable nanomaterials for phototherapy of cancer.BIOMEDICAL MATERIALS,16(4),11.
MLA	Zhou, Mengjiao,et al."Stimuli-activatable nanomaterials for phototherapy of cancer".BIOMEDICAL MATERIALS 16.4(2021):11.