Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes

doi:10.3390/molecules24010164

	Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes
	Zhao, Fei 1; Li, Pinyi 1; Liu, Xiaoyan 1; Jia, Xiuwen 1; Wang, Jiang 2,3,4; Liu, Hong 2,3,4
刊名	MOLECULES
	2019
卷号	24 期号:1 页码:22
关键词	amide bond sulfonamide bond alkynes addition reaction aminoacylation aminosulfonylation
ISSN号	1420-3049
DOI	10.3390/molecules24010164
通讯作者	Liu, Hong(hliu@simm.ac.cn)
英文摘要	The addition of amide/sulfonamide bonds to alkynes is not only one of the most important strategies for the direct functionalization of carbon-carbon triple bonds, but also a powerful tool for the downstream transformations of amides/sulfonamides. The present review provides a comprehensive summary of amide/sulfonamide bond addition to alkynes, including direct and metal-free aminoacylation, based-promoted aminoacylation, transition-metal-catalyzed aminoacylation, organocatalytic aminoacylation and transition-metal-catalyzed aminosulfonylation of alkynes up to December 2018. The reaction conditions, regio- and stereoselectivities, and mechanisms are discussed and summarized in detail.
资助项目	National Natural Science Foundation of China[21602022] ; National Natural Science Foundation of China[81620108027] ; National Natural Science Foundation of China[21632008] ; Sichuan Science and Technology Program[2018JY0345] ; Chengdu University New Faculty Start-up Funding[2081915037]
WOS关键词	C-N BOND ; METAL-CATALYZED REACTIONS ; ONE-POT SYNTHESIS ; HETEROATOM BONDS ; INDOLES ; PLATINUM ; 6-SULFONYLINDOLES ; CYCLIZATION ; CHEMISTRY ; KETONES
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:000457150200164
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/290693]
专题	中国科学院上海药物研究所
通讯作者	Liu, Hong
作者单位	1.Chengdu Univ, Sichuan Ind Inst Antibiot, Antibiot Res & Reevaluat Key Lab Sichuan Prov, 168 Hua Guan Rd, Chengdu 610052, Sichuan, Peoples R China 2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, CAS Key Lab Receptor Res, Shanghai Inst Mat Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 4.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Fei,Li, Pinyi,Liu, Xiaoyan,et al. Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes[J]. MOLECULES,2019,24(1):22.
APA	Zhao, Fei,Li, Pinyi,Liu, Xiaoyan,Jia, Xiuwen,Wang, Jiang,&Liu, Hong.(2019).Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes.MOLECULES,24(1),22.
MLA	Zhao, Fei,et al."Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes".MOLECULES 24.1(2019):22.