Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source

doi:10.1007/s00706-018-2331-7

	Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source
	Lyu, Xue 1,2; Sun, Guanglong 1,2; Zhou, Yang 1,2; Wang, Yingying 1,2; Lei, Min 1,2; Wu, Wanying 1,2; Guo, Dean 1,2
刊名	MONATSHEFTE FUR CHEMIE
	2019-02-01
卷号	150 期号:2 页码:309-315
关键词	Sonogashira cross-coupling Aryl iodide Alkyne Palladium Alkynones
ISSN号	0026-9247
DOI	10.1007/s00706-018-2331-7
通讯作者	Lei, Min(mlei@simm.ac.cn) ; Wu, Wanying(wanyingwu@simm.ac.cn)
英文摘要	A practical and efficient palladium-catalyzed carbonylative Sonogashira cross-coupling reaction for the synthesis of alkynones from aryl iodides, alkynes, and formic acid as the CO source has been described. Under the assistance of PPh3/I-2, formic acid can be used as the CO source for synthesis of alkynones in moderate-good yields. Furthermore, it is also successfully applied for the modification of natural products, such as vindoline and tabersonin, to obtain the corresponding products. [GRAPHICS] .
资助项目	Special Fund for Strategic Pilot Technology Chinese Academy of Sciences[XDA12040303]
WOS关键词	ARYL HALIDES ; 3-COMPONENT SYNTHESIS ; EFFICIENT SYNTHESIS ; TERMINAL ALKYNES ; CONVENIENT ; IODIDES ; AMINOCARBONYLATION ; HYDROXYCARBONYLATION ; CYCLOISOMERIZATION ; ACETYLENES
WOS研究方向	Chemistry
语种	英语
出版者	SPRINGER WIEN
WOS记录号	WOS:000457316200016
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/290636]
专题	中国科学院上海药物研究所
通讯作者	Lei, Min; Wu, Wanying
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Lyu, Xue,Sun, Guanglong,Zhou, Yang,et al. Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source[J]. MONATSHEFTE FUR CHEMIE,2019,150(2):309-315.
APA	Lyu, Xue.,Sun, Guanglong.,Zhou, Yang.,Wang, Yingying.,Lei, Min.,...&Guo, Dean.(2019).Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source.MONATSHEFTE FUR CHEMIE,150(2),309-315.
MLA	Lyu, Xue,et al."Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source".MONATSHEFTE FUR CHEMIE 150.2(2019):309-315.