PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides

doi:10.1016/j.tet.2019.01.023

	PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides
	Wang, Yingying 1,2; Zhou, Yang 1,2; Lei, Min 1,2; Hou, Jinjun 1,2; Jin, Qinghao 1,2; Guo, Dean 1,2; Wu, Wanying 1,2
刊名	TETRAHEDRON
	2019-03-01
卷号	75 期号:9 页码:1180-1185
关键词	Phthalimide PPh3/I-2/HCOOH 2-lodobenzamide Pd(OAc)(2) CO source
ISSN号	0040-4020
DOI	10.1016/j.tet.2019.01.023
通讯作者	Lei, Min(mlei@simm.ac.cn) ; Wu, Wanying(wanyingwu@simm.ac.cn)
英文摘要	A straightforward and general method has been developed for the synthesis of phthalimide derivatives from 2-iodobenzamides and PPh3/I-2/HCOOH in the presence of a catalytic amount of Pd(OAc)(2). The reaction results demonstrate that PPh3/I-2/HCOOH is a facile, efficient and safe CO source. The whole process is carried out in toluene at 80 degrees C and furnishes the desired products in good to excellent yields. (C) 2019 Published by Elsevier Ltd.
资助项目	Special Fund for Strategic Pilot Technology Chinese Academy of Sciences[XDA12020379]
WOS关键词	PALLADIUM-CATALYZED SYNTHESIS ; REDUCTIVE CARBONYLATION ; DIRECT FORMYLATION ; AROMATIC IODIDES ; ARYL IODIDES ; ALDEHYDES ; ACID ; NITROGEN
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000459522800009
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/290462]
专题	中国科学院上海药物研究所
通讯作者	Lei, Min; Wu, Wanying
作者单位	1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yingying,Zhou, Yang,Lei, Min,et al. PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides[J]. TETRAHEDRON,2019,75(9):1180-1185.
APA	Wang, Yingying.,Zhou, Yang.,Lei, Min.,Hou, Jinjun.,Jin, Qinghao.,...&Wu, Wanying.(2019).PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides.TETRAHEDRON,75(9),1180-1185.
MLA	Wang, Yingying,et al."PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides".TETRAHEDRON 75.9(2019):1180-1185.