Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries

doi:10.1039/c9cc00440h

	Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries
	Feng, Lei 2,3; Yan, Qingsong 2,4; Zhang, Baojing 2; Tian, Xiangge 2,4; Wang, Chao 2,3; Yu, Zhenlong 2; Cui, Jingnan 3; Guo, Dean 4; Ma, Xiaochi 2,4; James, Tony D.1
刊名	CHEMICAL COMMUNICATIONS
	2019-03-25
卷号	55 期号:24 页码:3548-3551
ISSN号	1359-7345
DOI	10.1039/c9cc00440h
通讯作者	Wang, Chao(wach_edu@sina.com) ; Guo, Dean(daguo@simm.ac.cn) ; James, Tony D.(t.d.james@bath.ac.uk)
英文摘要	We report on a naphthalimide ratiometric fluorescent probe for the real-time sensing and imaging of pathogenic bacterial glucosyltransferases, which are associated with the development of dental caries. Using a high-throughput screening method, we identified that several natural polyphenols from green tea were GTFs inhibitors that could eventually lead to suitable oral treatments to prevent the development of dental caries.
资助项目	National Natural Science Foundation of China[81622047] ; National Natural Science Foundation of China[81872970] ; National Natural Science Foundation of China[81503240] ; State Key Laboratory of Fine Chemicals[KF1803] ; State Key Laboratory of Fine Chemicals[KF1705] ; Program for High-level Talents of Dalian City[2017RQ119] ; Royal Society
WOS关键词	BETA-GLUCURONIDASE ; LIVING CELLS ; ENZYME
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000462654300024
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/290156]
专题	中国科学院上海药物研究所
通讯作者	Wang, Chao; Guo, Dean; James, Tony D.
作者单位	1.Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England 2.Dalian Med Univ, Natl & Local Joint Engn Res Ctr Drug Dev Neurodeg, Acad Integrat Med, Coll Pharm, Dalian 116044, Peoples R China 3.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 4.Chinese Acad Sci, Natl Engn Lab TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Feng, Lei,Yan, Qingsong,Zhang, Baojing,et al. Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries[J]. CHEMICAL COMMUNICATIONS,2019,55(24):3548-3551.
APA	Feng, Lei.,Yan, Qingsong.,Zhang, Baojing.,Tian, Xiangge.,Wang, Chao.,...&James, Tony D..(2019).Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries.CHEMICAL COMMUNICATIONS,55(24),3548-3551.
MLA	Feng, Lei,et al."Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries".CHEMICAL COMMUNICATIONS 55.24(2019):3548-3551.