Response of microorganisms in biofilm to sulfadiazine and ciprofloxacin in drinking water distribution systems

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院饮用水科学与技术重点实验室

	Response of microorganisms in biofilm to sulfadiazine and ciprofloxacin in drinking water distribution systems
	Wang, Haibo ; Hu, Chun ; Shen, Yi ; Shi, Baoyou ; Zhao, Dan ; Xing, Xueci
刊名	CHEMOSPHERE
	2019-03-01
卷号	218 页码:197-204
关键词	Sulfadiazine Ciprofloxacin Biofilm Antibiotic resistance genes Enzymatic activities Extracellular polymeric substances
ISSN号	0045-6535
英文摘要	Effects of sulfadiazine and ciprofloxacin on microorganisms in biofilm of drinking water distribution systems (DWDSs) were studied. The results verified that the increases of 16S rRNA for total bacteria and bacterial genus Hyphomicrobium were related to the promotion of antibiotic resistance genes (ARGs) and class 1 integrons (int1) in DWDSs with sulfadiazine and ciprofloxacin. Moreover, the bacteria showed higher enzymatic activities in DWDSs with sulfadiazine and ciprofloxacin, which resulted in more production of extracellular polymeric substances (EPS). The higher contents of EPS proteins and secondary structure beta-sheet promoted bacterial aggregation and adsorption onto surface of pipelines to form biofilm. EPS can serve as a barrier for the microorganisms in biofilm. Therefore, the biofilm bacterial communities shifted and the 16S rRNA for total bacteria increased in DWDSs with antibiotics, which also drove the ARGs promotion. Furthermore, the two antibiotics exhibited stronger combined effects than that caused by sulfadiazine and ciprofloxacin alone. (C) 2018 Published by Elsevier Ltd.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/43518]
专题	生态环境研究中心_中国科学院饮用水科学与技术重点实验室
作者单位	1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Key Lab Drinking Water Sci & Technol, Beijing 100085, Peoples R China 2.Guangzhou Univ, Key Lab Water Qual & Conservat Pearl River Delta, Minist Educ, Inst Environm Res Greater Bay, Guangzhou 510006, Guangdong, Peoples R China 3.Suzhou Univ Sci & Technol, Sch Environm Sci & Engn, Suzhou 215009, Jiangsu, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Haibo,Hu, Chun,Shen, Yi,et al. Response of microorganisms in biofilm to sulfadiazine and ciprofloxacin in drinking water distribution systems[J]. CHEMOSPHERE,2019,218:197-204.
APA	Wang, Haibo,Hu, Chun,Shen, Yi,Shi, Baoyou,Zhao, Dan,&Xing, Xueci.(2019).Response of microorganisms in biofilm to sulfadiazine and ciprofloxacin in drinking water distribution systems.CHEMOSPHERE,218,197-204.
MLA	Wang, Haibo,et al."Response of microorganisms in biofilm to sulfadiazine and ciprofloxacin in drinking water distribution systems".CHEMOSPHERE 218(2019):197-204.