Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境水质学国家重点实验室

	Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?
	Li, Na ; Ho, Wingkei ; Wu, Rudolf Shiu Sun ; Ying, Guang-Guo ; Wang, Zijian ; Jones, Kevin ; Deng, Wen-Jing
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2019-11-15
卷号	183 页码:-
关键词	Organophosphate flame retardants Children burden Urine Children exposure
ISSN号	0147-6513
英文摘要	The urine levels of organophosphate flame retardants (PFRs) and bisphenol A (BPA) in kindergarten children (n = 31, 4-6 years old, sampling performed in 2016) in Hong Kong were measured. The detection frequency of the target PFRs, tri(2-chloroethyl)phosphate (TCEP), tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), tris (chloroisopropyl)phosphate (TCIPP), diphenyl phosphate (TPHP) and 2-ethylhexyl diphenyl phosphate (EHDPP) ranged from 52% to 84%. The 95th percentile urinary concentrations of TPHP, TDCIPP, TCIPP, EHDPP and TCEP were 1.70, 0.24, 0.03, 0.05, 0.68 and 0.03 ng/mL, respectively. The median urine level of BPA was 1.69 ng/mL, with a detection frequency of 77%. Due to the lack of metabolism information, two scenarios were used to calculate the estimated daily intake (EDI) of these compounds. Back-calculated EDIs of PFRs using the urinary excretion rates from in vivo animal data (scenario 2) were up to 2.97 mu g/kg/d (TDCIPP), which was only a little less than that observed in a sample of American infants, and the reference dose (RID), meaning that the potential health risk of TDCIPP cannot be ignored. Dust ingestion was suggested to be the major pathway of exposure to PFRs, but when the levels in dust and air particles in kindergartens in Hong Kong were used to predict EDIs, these values were nearly half as much as those predicted from urinary TDCIPP in this study. This suggested that children's PFRs burden may be underestimated when considering only PFR levels in dust or air. There is thus a need for further studies with large-scale surveys and investigation of exposure routes.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/42664]
专题	生态环境研究中心_环境水质学国家重点实验室
作者单位	1.Educ Univ Hong Kong, Dept Sci & Environm Studies, Tai Po, Hong Kong, Peoples R China 2.South China Normal Univ, Environm Res Inst, MOE Key Lab Environm Theoret Chem, Guangzhou, Guangdong, Peoples R China 3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Aquat Chem, Beijing 100085, Peoples R China
推荐引用方式 GB/T 7714	Li, Na,Ho, Wingkei,Wu, Rudolf Shiu Sun,et al. Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2019,183:-.
APA	Li, Na.,Ho, Wingkei.,Wu, Rudolf Shiu Sun.,Ying, Guang-Guo.,Wang, Zijian.,...&Deng, Wen-Jing.(2019).Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,183,-.
MLA	Li, Na,et al."Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 183(2019):-.