Acute and Sublethal Effects of Ethylmercury Chloride on Chinese Rare Minnow (Gobiocypris rarus): Accumulation, Elimination, and Histological Changes
Cao, Dandan; He, Bin; Yin, Yongguang
刊名BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
2019-05
卷号102期号:5页码:708-713
关键词Ethylmercury Chinese rare minnow Histopathological change Bioaccumulation Elimination
ISSN号0007-4861
英文摘要Ethylmercury (EtHg) has been widely observed in the environment due to anthropogenic contamination and/or environmental ethylation of inorganic mercury. Herein, the acute and sublethal effect of EtHg chloride on Chinese rare minnow (Gobiocypris rarus) as a fish model was studied. EtHg chloride showed an obvious toxicity to 4-month-old Chinese rare minnow (LC50 24.8 mu gL(-1) (as Hg) at 24h). Histological analysis revealed that acute EtHg exposure can induce necrosis, telangiectasis and exfoliation of epithelial cells in the gill, as well as edema, vacuoles, and pyknotic nuclei in hepatocytes. Sublethal dose exposure revealed a very high accumulation of EtHg in fish, which is subsequently metabolized to inorganic mercury and eliminated after depuration. A new mercury species, possibly diethylmercury, was also observed as the metabolite of EtHg in rare minnow. The present study provides useful information for assessing the risks of EtHg and understanding its bioaccumulation in aquatic organisms.
内容类型期刊论文
源URL[http://ir.rcees.ac.cn/handle/311016/42889]  
专题生态环境研究中心_环境化学与生态毒理学国家重点实验室
作者单位1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Lab Environm Nanotechnol & Hlth, Beijing 100085, Peoples R China
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Cao, Dandan,He, Bin,Yin, Yongguang. Acute and Sublethal Effects of Ethylmercury Chloride on Chinese Rare Minnow (Gobiocypris rarus): Accumulation, Elimination, and Histological Changes[J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,2019,102(5):708-713.
APA Cao, Dandan,He, Bin,&Yin, Yongguang.(2019).Acute and Sublethal Effects of Ethylmercury Chloride on Chinese Rare Minnow (Gobiocypris rarus): Accumulation, Elimination, and Histological Changes.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,102(5),708-713.
MLA Cao, Dandan,et al."Acute and Sublethal Effects of Ethylmercury Chloride on Chinese Rare Minnow (Gobiocypris rarus): Accumulation, Elimination, and Histological Changes".BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 102.5(2019):708-713.
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