Label-free measurements on the solution of monomeric and dimeric insulin using a periodical terahertz split ring resonator

doi:10.1016/j.chemphys.2019.05.017

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Label-free measurements on the solution of monomeric and dimeric insulin using a periodical terahertz split ring resonator
	Wang, PF ; Liu, LY ; Wang, XC ; Zhang, JB ; Qi, W ; Zhao, HW ; Tian, Z ; He, MX
刊名	CHEMICAL PHYSICS
	2019
卷号	525 页码:-
关键词	PULSED SPECTROSCOPY METAMATERIAL DISSOCIATION AGGREGATION FILTER
ISSN号	0301-0104
DOI	10.1016/j.chemphys.2019.05.017
文献子类	期刊论文
英文摘要	A silicon-based sensor, consisting of periodical split ring resonators was demonstrated to monitor monomeric and dimeric insulin solutions in terahertz time-domain spectroscopy (THz-TDS). As concentration increases, the resonant frequencies of sensor show red shifts with a rapid trend in dilute solutions and a slow trend in concentrated solutions, consistent with CST simulations. For monomeric insulin, the turning concentration is 11.6 mg/ml and the total frequency shift is larger than that of dimeric insulin which shows a turning concentration at 17.4 mg/ml. The deviation in frequency shift and turning concentration can be attributed to the structural changes of insulin during dimerization process.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/32112]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Chinese Acad Sci, Div Interfacial Water, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China; 2.Chinese Acad Sci, Key Lab Interfacial Phys & Technol, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China 3.Tianjin Univ, State Key Lab Precis Measuring Technol & Instrume, Tianjin 300072, Peoples R China; 4.Tianjin Univ, Key Lab Optoelect Informat & Tech Sci, Minist Educ China, Tianjin 300072, Peoples R China; 5.Tianjin Univ, State Key Lab Chem Engn, Tianjin 300072, Peoples R China;
推荐引用方式 GB/T 7714	Wang, PF,Liu, LY,Wang, XC,et al. Label-free measurements on the solution of monomeric and dimeric insulin using a periodical terahertz split ring resonator[J]. CHEMICAL PHYSICS,2019,525:-.
APA	Wang, PF.,Liu, LY.,Wang, XC.,Zhang, JB.,Qi, W.,...&He, MX.(2019).Label-free measurements on the solution of monomeric and dimeric insulin using a periodical terahertz split ring resonator.CHEMICAL PHYSICS,525,-.
MLA	Wang, PF,et al."Label-free measurements on the solution of monomeric and dimeric insulin using a periodical terahertz split ring resonator".CHEMICAL PHYSICS 525(2019):-.