Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches

doi:10.1039/c9nr05234h

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches
	Liu, WJ ; Guo, YR ; Wang, KZ ; Zhou, XF ; Wang, Y ; Lu, JH ; Shao, ZF ; Hu, J ; Czajkowsky, DM ; Li, B
刊名	NANOSCALE
	2019
卷号	11 期号:37 页码:17206-17210
关键词	RESOLUTION RECOGNITION MECHANICS PROTEINS
ISSN号	2040-3364
DOI	10.1039/c9nr05234h
文献子类	期刊论文
英文摘要	Atomic force microscopy-based single-molecule-force spectroscopy is limited by low throughput. We introduce addressable DNA origami to study multiple target molecules. Six target DNAs that differed by only a single base-pair mismatch were clearly differentiated a rupture force of only 4 pN.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/31967]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Shanghai Tech Univ, Sch Phys Sci & Technol, Shanghai 201204, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 4.Ningbo Univ, Sch Sci, Ningbo 315211, Zhejiang, Peoples R China; 5.Shanghai Jiao Tong Univ, Sch Biomed Engn, BioID Ctr, Shanghai 200240, Peoples R China; 6.Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Shanghai 201210, Peoples R China;
推荐引用方式 GB/T 7714	Liu, WJ,Guo, YR,Wang, KZ,et al. Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches[J]. NANOSCALE,2019,11(37):17206-17210.
APA	Liu, WJ.,Guo, YR.,Wang, KZ.,Zhou, XF.,Wang, Y.,...&Li, B.(2019).Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches.NANOSCALE,11(37),17206-17210.
MLA	Liu, WJ,et al."Atomic force microscopy-based single-molecule force spectroscopy detects DNA base mismatches".NANOSCALE 11.37(2019):17206-17210.