The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety | |
Zhong, Yinghua1; Hu, Manji1; Wang, Qiang1; Yang, Zhendong1; Zhu, Na1; Wang, Fei1; Zhang, Xiyan1; Zhang, Chengfang1; Min, Jie1; Wang, Hao1 | |
刊名 | SCIENTIFIC REPORTS |
2021-02-08 | |
卷号 | 11期号:1页码:9 |
ISSN号 | 2045-2322 |
DOI | 10.1038/s41598-021-81653-2 |
产权排序 | 3 |
文献子类 | 实证研究 |
英文摘要 | Metabolic syndrome (MetS) is associated with depression, but its role in major depressive disorder comorbid with anxiety (AMD) is unclear. This study aimed to investigate the prevalence and clinical correlates of MetS in first-episode drug-naive (FEDN) patients with AMD in a Chinese Han population. In total, 1380 FEDN outpatients with AMD were recruited in this cross-sectional study. The sociodemographic features, clinical characteristics, history of suicide attempts, thyroid-stimulating hormone (TSH) levels, and MetS parameters of each subject were evaluated. All subjects were rated on the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and the Positive and Negative Syndrome Scale positive symptom subscale. The prevalence of MetS among AMD patients was 8.04%. Compared to the non-MetS group, age, age of onset, TSH level, HAM-A and HAM-D scores, history of attempted suicide, and comorbid psychiatric symptoms were higher in the MetS group. Those in this group were also more likely to be married, and they had a lower educational level. Furthermore, age, psychiatric symptoms, suicide attempts, and higher TSH levels were independently associated with MetS in AMD patients. This study suggests a lower prevalence of MetS in FEDN patients with AMD in a Chinese Han population. Older age, comorbid psychiatric symptoms, history of attempted suicide, and higher TSH levels are related factors for MetS in AMD patients. |
资助项目 | National Natural Science Foundation of China[81771464] ; Training Plan of Health System Academic Leader of the Shanghai Pudong Municipality Health Commission[PWRd2019-08] ; Outstanding Clinical Discipline Project of Shanghai Pudong[PWYgy2018-10] ; Hospital Level Project of Shanghai Pudong New Area Mental Health Center[PDJWM201903] ; General Project of the Shanghai Municipality Health Commission[202040475] |
WOS研究方向 | Science & Technology - Other Topics |
出版者 | NATURE RESEARCH |
WOS记录号 | WOS:000617646300009 |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/38546] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Zhao, Xudong; Zhang, Xiangyang |
作者单位 | 1.Tongji Univ, Shanghai Pudong New Area Mental Hlth Ctr, Sch Med, Shanghai, Peoples R China 2.Tongji Univ, Sch Med, Div Med Humanities & Behav Sci, 1239 Siping Rd,Postbox 244, Shanghai 200092, Peoples R China 3.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China |
推荐引用方式 GB/T 7714 | Zhong, Yinghua,Hu, Manji,Wang, Qiang,et al. The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety[J]. SCIENTIFIC REPORTS,2021,11(1):9. |
APA | Zhong, Yinghua.,Hu, Manji.,Wang, Qiang.,Yang, Zhendong.,Zhu, Na.,...&Zhang, Xiangyang.(2021).The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety.SCIENTIFIC REPORTS,11(1),9. |
MLA | Zhong, Yinghua,et al."The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety".SCIENTIFIC REPORTS 11.1(2021):9. |
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