Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression | |
Li, Hehua2; Huang, Yuanyuan2; Wu, Fengchun2,3; Lang, XiaoE4; Zhang, Xiang Yang1,2,5 | |
刊名 | JOURNAL OF AFFECTIVE DISORDERS |
2020-06-01 | |
卷号 | 270页码:108-113 |
关键词 | Major depressive disorder Psychotic symptom Suicide attempts Prevalence Correlates |
ISSN号 | 0165-0327 |
DOI | 10.1016/j.jad.2020.03.093 |
产权排序 | 3 |
文献子类 | Article |
英文摘要 | Background: Major depressive depression (MDD) is often accompanied by suicidal behavior. Increasing evidence shows that MDD patients display psychotic symptoms. However, the relationship between psychotic symptoms and suicide attempt in MDD has not been reported. Therefore, this study was to identify the prevalence and associated factors of suicide attempts in first-episode and untreated Chinese Han outpatients comorbid with psychotic major depression (PMD). Methods: 1718 first-episode and untreated MDD outpatients were assessed with Positive Symptom Scale of Positive and Negative Syndrome Scale (PANSS), the 17-item Hamilton Depression Scale, Hamilton Anxiety Scale, and clinical global impression of severity scale (CGI-S). Some glycolipid metabolism and thyroid hormone parameters were measured. Results: In MDD patients, the percentage of PMD was 10.0%. The incidence of attempted suicide in PMD patients was 51.5%, which was more than 3 times higher than that in non-PMD patients (16.7%). In PMD patients, compared to non-attempters, suicide attempters were older, had a longer course of disease, scored higher on all scales, as well as had higher levels of thyroid stimulating hormone (TSH), thyroid peroxidases antibody, antithyroglobulin and blood glucose. PANSS positive symptom, CGI, diastolic blood pressure and TSH were independently associated with suicide attempts of PMD. Conclusions: PMD patients have a higher prevalence of suicide attempt than non-PMD patients. Some demographic and clinical parameters are relevant factors for suicide attempt in PMD patients. |
资助项目 | National Natural Science Foundation of China[31771074] ; Scientific research project of traditional Chinese medicine of Guangdong[20192070] ; Science and technology project of Liwan district[201804011] ; Science and Technology Program of Guangzhou[201807010064] ; Science and Technology Program of Guangzhou[201704020168] ; Science and Technology Program of Guangzhou[201804010259] |
WOS关键词 | RISK-FACTORS ; OLDER-PEOPLE ; FEATURES ; DISORDERS ; DELUSIONS ; DIAGNOSIS ; VALIDITY ; IDEATION ; AGE |
WOS研究方向 | Neurosciences & Neurology ; Psychiatry |
语种 | 英语 |
出版者 | ELSEVIER |
WOS记录号 | WOS:000529319400018 |
资助机构 | National Natural Science Foundation of China ; Scientific research project of traditional Chinese medicine of Guangdong ; Science and technology project of Liwan district ; Science and Technology Program of Guangzhou |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/31729] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Wu, Fengchun; Zhang, Xiang Yang |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 2.Guangzhou Med Univ, Dept Psychiat, Affiliated Brain Hosp, Guangzhou Huiai Hosp, Guangzhou, Peoples R China 3.Guangdong Engn Technol Res Ctr Translat Med Menta, Guangzhou, Peoples R China 4.Shanxi Med Univ, Clin Med Coll 1, Dept Psychiat, Taiyuan, Shanxi, Peoples R China 5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Hehua,Huang, Yuanyuan,Wu, Fengchun,et al. Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression[J]. JOURNAL OF AFFECTIVE DISORDERS,2020,270:108-113. |
APA | Li, Hehua,Huang, Yuanyuan,Wu, Fengchun,Lang, XiaoE,&Zhang, Xiang Yang.(2020).Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression.JOURNAL OF AFFECTIVE DISORDERS,270,108-113. |
MLA | Li, Hehua,et al."Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression".JOURNAL OF AFFECTIVE DISORDERS 270(2020):108-113. |
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