Synthesis of gold-silica core-shell nanoparticles by pulsed laser ablation in liquid and their physico-chemical properties towards photothermal cancer therapy

doi:10.1039/c9nr07129f

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2020专题

	Synthesis of gold-silica core-shell nanoparticles by pulsed laser ablation in liquid and their physico-chemical properties towards photothermal cancer therapy
	Riedel, Rene ; Mahr, Nora ; Yao, Chenyang ; Wu, Aiguo ; Yang, Fang ; Hampp, Norbert
刊名	NANOSCALE
	2020
卷号	12 期号:5 页码:3007-3018
关键词	ONE-POT SYNTHESIS IN-VIVO MESOPOROUS SILICA SURFACE NANOSPHERES ENDOCYTOSIS CIRCULATION ELASTICITY MECHANISMS RESONANCE
DOI	10.1039/c9nr07129f
英文摘要	Due to the increasing scientific and biomedical interest in various nanoparticles (NPs) with excellent properties and the onset of their commercial use, a convenient and adjustable physical method for improved efficiency needs to be used for enabling their tech-scale production. Recently, great progress has been made in the large-scale production of NPs with a simple structure by pulsed laser ablation in liquid (PLAL). In this work, we synthesized gold-silica core-shell NPs by improved PLAL and provided a guide on how to investigate their physico-chemical properties and association with biological effects towards cancer photothermal therapy (PTT). By means of this method, reproducible and scalable liquid phase NPs with less toxicity and good stability can be realized for tech-scale production based on its further adjustment and modification. Moreover, a more complete investigation of the associations between the physicochemical properties of functional NPs with complex structure and their biological effects may enable more targeted NPs towards specific requirements of biomedical applications.
学科主题	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/19991]
专题	2020专题
作者单位	1.Yang, F 2.Hampp, N (corresponding author), Univ Marburg, Phys Chem Dept, Marburg, Germany. 3.Yang, F (corresponding author), Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Cixi Inst Biomed Engn, CAS Key Lab Magnet Mat & Devices, Ningbo 315201, Peoples R China. 4.Yang, F (corresponding author), Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Key Lab Addit Mfg Mat Zhejiang Prov, Ningbo 315201, Peoples R China.
推荐引用方式 GB/T 7714	Riedel, Rene,Mahr, Nora,Yao, Chenyang,et al. Synthesis of gold-silica core-shell nanoparticles by pulsed laser ablation in liquid and their physico-chemical properties towards photothermal cancer therapy[J]. NANOSCALE,2020,12(5):3007-3018.
APA	Riedel, Rene,Mahr, Nora,Yao, Chenyang,Wu, Aiguo,Yang, Fang,&Hampp, Norbert.(2020).Synthesis of gold-silica core-shell nanoparticles by pulsed laser ablation in liquid and their physico-chemical properties towards photothermal cancer therapy.NANOSCALE,12(5),3007-3018.
MLA	Riedel, Rene,et al."Synthesis of gold-silica core-shell nanoparticles by pulsed laser ablation in liquid and their physico-chemical properties towards photothermal cancer therapy".NANOSCALE 12.5(2020):3007-3018.