Spatial association between outdoor air pollution and lung cancer incidence in China

doi:10.1186/s12889-019-7740-y

	Spatial association between outdoor air pollution and lung cancer incidence in China
	Xing,D. F.1,2; Xu,C. D.1; Liao,X. Y.3; Xing,T. Y.2; Cheng,S. P.4; Hu,M. G.1; Wang,J. X.1
刊名	BMC Public Health
	2019-10-26
卷号	19 期号:1
关键词	Lung cancer Outdoor air pollution GeoDetector Spatial association Smoking
ISSN号	1471-2458
DOI	10.1186/s12889-019-7740-y
通讯作者	Xu,C. D.(xucd@lreis.ac.cn) ; Liao,X. Y.(liaoxy@igsnrr.ac.cn)
英文摘要	AbstractBackgroundLung cancer is the most common cancer in China. Previous studies have indicated that lung cancer incidence exhibits remarkable spatial heterogeneity, and lung cancer is related to outdoor air pollution. However, the non-linear spatial association between outdoor air pollution and lung cancer incidence in China remains unclear.MethodsIn this study, the relationships between the lung cancer incidence of males and females from 207 counties in China in 2013 with annual concentrations of PM2.5, PM10, SO2, NO2, CO and O3 were analysed. GeoDetector q statistic was used for examining the non-linear spatial association between outdoor air pollution and incidence of lung cancer.ResultsAn apparent spatial and population gender heterogeneity was found in the spatial association between outdoor air pollution and lung cancer incidence. Among the six selected pollutants, SO2 has the greatest influence on lung cancer (q?=?0.154 in females) in north China. In the south, each selected pollutant has a significant impact on males or females, and the mean q value in the south is 0.181, which is bigger than that in the north (q?=?0.154). In addition, the pollutants have evident non-linear interaction effects on lung cancer. In north China, the interaction between SO2 and PM2.5 is the dominant interaction, with q values of 0.207 in males and 0.334 in females. In the south, the dominant interactive factors are between SO2 and O3 in males and between SO2 and CO in females, with q values of 0.45, 0.232 respectively. Smoking is a substantial contributor to lung cancer among men, either in South or North China, with q value of 0.143 and 0.129 respectively, and the interaction between smoking and air pollutants increases this risk.ConclusionsThis study implies that the influence of SO2 and PM2.5 on lung cancer should be focused on in north China, and in the south, the impact of O3 and CO as well as their interaction with SO2 need to be paid more attention. Smoking, particularly in men, remains a significant risk factor for lung cancer in both North and South China.
语种	英语
出版者	BioMed Central
WOS记录号	BMC:10.1186/S12889-019-7740-Y
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/69589]
专题	中国科学院地理科学与资源研究所
通讯作者	Xu,C. D.; Liao,X. Y.
作者单位	1. 2. 3. 4.
推荐引用方式 GB/T 7714	Xing,D. F.,Xu,C. D.,Liao,X. Y.,et al. Spatial association between outdoor air pollution and lung cancer incidence in China[J]. BMC Public Health,2019,19(1).
APA	Xing,D. F..,Xu,C. D..,Liao,X. Y..,Xing,T. Y..,Cheng,S. P..,...&Wang,J. X..(2019).Spatial association between outdoor air pollution and lung cancer incidence in China.BMC Public Health,19(1).
MLA	Xing,D. F.,et al."Spatial association between outdoor air pollution and lung cancer incidence in China".BMC Public Health 19.1(2019).