Multi-emitting fluorescence sensor of MnO2-OPD-QD for the multiplex and visual detection of ascorbic acid and alkaline phosphatase

doi:10.1039/c9tc07072a

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Multi-emitting fluorescence sensor of MnO2-OPD-QD for the multiplex and visual detection of ascorbic acid and alkaline phosphatase
	Yang, Qian 1,5; Li, Chuyao 1,5; Li, Jinhua 1; Arabi, Maryam 1; Wang, Xiaoyan 1,2; Peng, Hailong 5; Xiong, Hua 5; Choo, Jaebum 3; Chen, Lingxin 1,2,4
刊名	JOURNAL OF MATERIALS CHEMISTRY C
	2020-04-28
卷号	8 期号:16 页码:5554-5561
ISSN号	2050-7526
DOI	10.1039/c9tc07072a
通讯作者	Xiong, Hua(huaxiong100@126.com) ; Choo, Jaebum(jbchoo@cau.ac.kr) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	A blue-, yellow- and red-emitting fluorescence sensor was constructedviathe synergy of manganese dioxide (MnO2) nanosheets,o-phenylenediamine (OPD) and red-fluorescent quantum dots (r-QDs), namely MnO2-OPD-QD, for visualization of ascorbic acid (AA) and alkaline phosphatase (ALP). Initially, by virtue of the oxidase-like activity of MnO(2)nanosheets, OPD was oxidized into yellow-fluorescent OPDox (emission: 569 nm), which quenched the r-QDs (emission: 659 nm). After interaction with AA, one reaction product of ALP and 2-phospho-l-ascorbic acid (AA2P), the MnO(2)nanosheets were reduced and lost the oxidase-like activity, so that the generation of OPDox was lessened and the fluorescence of the r-QDs was thereupon recovered. Further increasing AA or ALP, the MnO(2)nanosheets were fully decomposed so that OPD was not oxidized but was reduced into blue-fluorescent OPDred (emission: 441 nm), while the r-QDs were not affected. Overall, AA or ALP triggered emission intensity changes at 441, 569 and 659 nm and led to profuse color variation over the yellow-orange-red-purple range, realizing multiplex and visual determination of AA and ALP in the ranges of 0.5-70 mu M and 0.1-100 mU mL(-1), respectively. The color variation range of the ternary-emission mode was greatly enlarged, especially compared with that of the single-/dual-emission mode. Accordingly, the MnO2-OPD-QD sensor provided detection limits for AA and ALP as low as 0.18 mu M and 0.06 mU mL(-1), respectively. Furthermore, the highly selective/sensitive measurement and accurate readout of AA and ALP were accomplished in complicated food and serum samples. The multi-emitting fluorescence sensor held great potential for onsite visualization of various targets in more fields.
资助项目	National Natural Science Foundation of China[21667018] ; National Natural Science Foundation of China[31860470] ; National Natural Science Foundation of China[21876199] ; National Natural Science Foundation of China[21804010] ; National Natural Science Foundation of China[21976209] ; National Natural Science Foundation of China[31660482] ; Chinese Academy of Sciences President's International Fellowship Initiative[2019PC0050] ; National Research Foundation of Korea[2019R1A2C3004375] ; National Research Foundation of Korea[2018M3A7B4071203] ; Taishan Scholar Project Special Fund[ts20190962]
WOS关键词	RATIOMETRIC FLUORESCENCE ; MNO2 NANOSHEETS ; POLYDOPAMINE NANOPARTICLES ; GLUTATHIONE DETECTION ; SENSING PLATFORM ; QUANTUM DOTS ; CARBON DOTS ; ASSAY
WOS研究方向	Materials Science ; Physics
语种	英语
WOS记录号	WOS:000547201400025
资助机构	National Natural Science Foundation of China ; Chinese Academy of Sciences President's International Fellowship Initiative ; National Research Foundation of Korea ; Taishan Scholar Project Special Fund
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/28653]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者	Xiong, Hua; Choo, Jaebum; Chen, Lingxin
作者单位	1.Chinese Acad Sci, Res Ctr Coastal Environm Engn & Technol, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 3.Chung Ang Univ, Dept Chem, Seoul 06974, South Korea 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 5.Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China
推荐引用方式 GB/T 7714	Yang, Qian,Li, Chuyao,Li, Jinhua,et al. Multi-emitting fluorescence sensor of MnO2-OPD-QD for the multiplex and visual detection of ascorbic acid and alkaline phosphatase[J]. JOURNAL OF MATERIALS CHEMISTRY C,2020,8(16):5554-5561.
APA	Yang, Qian.,Li, Chuyao.,Li, Jinhua.,Arabi, Maryam.,Wang, Xiaoyan.,...&Chen, Lingxin.(2020).Multi-emitting fluorescence sensor of MnO2-OPD-QD for the multiplex and visual detection of ascorbic acid and alkaline phosphatase.JOURNAL OF MATERIALS CHEMISTRY C,8(16),5554-5561.
MLA	Yang, Qian,et al."Multi-emitting fluorescence sensor of MnO2-OPD-QD for the multiplex and visual detection of ascorbic acid and alkaline phosphatase".JOURNAL OF MATERIALS CHEMISTRY C 8.16(2020):5554-5561.