ANN AND RSM BASED OPTIMIZATION OF CELLULASE PRODUCTION BY HYPOCREA SP Z28 BY SUBMERGED FERMENTATION

	ANN AND RSM BASED OPTIMIZATION OF CELLULASE PRODUCTION BY HYPOCREA SP Z28 BY SUBMERGED FERMENTATION
	Zhang, Yu 1,2; Zhang, Xiaohuan 1,2,3; Qi, Wei 1,2; Xu, Jingliang 1,2; Yuan, Zhenhong 1,2; Wang, Zhongming 1,2
刊名	CELLULOSE CHEMISTRY AND TECHNOLOGY
	2018-03-01
卷号	52 期号:3-4 页码:259-264
关键词	cellulase production submerged fermentation artificial neural network-genetic algorithm bioprocess optimization response surface methodology Hypocrea sp.
ISSN号	0576-9787
通讯作者	Xu, Jingliang(xjl@ms.giec.ac.cn)
英文摘要	Response surface methodology (RSM) and artificial neural network (ANN) were used to simulate and optimize cellulase production by Hypocrea sp. Z28 by submerged fermentation. Results showed ANN had higher simulation accuracy than RSM. Cellulase production optimized by RSM was 5.48 U/mL, while the corresponding experimental value was 5.67 +/- 0.32 U/mL. Using ANN as a prediction function, a maximum cellulase production of 5.96 U/mL was searched by the genetic algorithm, and the corresponding experimental value was 6.01 +/- 0.43 U/mL. Compared to RSM, ANN brought higher and more accurate cellulase production values. The application of ANN to optimize cellulase production proved successful.
资助项目	National Natural Science Foundation of China[21506215] ; National Natural Science Foundation of China[51561145015]
WOS关键词	RESPONSE-SURFACE METHODOLOGY ; ARTIFICIAL NEURAL-NETWORKS ; SOLID-STATE FERMENTATION ; DEXTRANICUM NRRL B-1146 ; EXOCELLULAR GLUCANSUCRASE ; MICROBIAL CELLULASES ; ENHANCED PRODUCTION ; MODELS ; STRAIN
WOS研究方向	Materials Science
语种	英语
出版者	EDITURA ACAD ROMANE
WOS记录号	WOS:000441008600012
资助机构	National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.giec.ac.cn/handle/344007/23697]
专题	中国科学院广州能源研究所
通讯作者	Xu, Jingliang
作者单位	1.Guangdong Prov Key Lab New & Renewable Energy Res, Guangzhou 510640, Guangdong, Peoples R China 2.Chinese Acad Sci, Key Lab Renewable Energy, Guangzhou Inst Energy Convers, Guangzhou 510640, Guangdong, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yu,Zhang, Xiaohuan,Qi, Wei,et al. ANN AND RSM BASED OPTIMIZATION OF CELLULASE PRODUCTION BY HYPOCREA SP Z28 BY SUBMERGED FERMENTATION[J]. CELLULOSE CHEMISTRY AND TECHNOLOGY,2018,52(3-4):259-264.
APA	Zhang, Yu,Zhang, Xiaohuan,Qi, Wei,Xu, Jingliang,Yuan, Zhenhong,&Wang, Zhongming.(2018).ANN AND RSM BASED OPTIMIZATION OF CELLULASE PRODUCTION BY HYPOCREA SP Z28 BY SUBMERGED FERMENTATION.CELLULOSE CHEMISTRY AND TECHNOLOGY,52(3-4),259-264.
MLA	Zhang, Yu,et al."ANN AND RSM BASED OPTIMIZATION OF CELLULASE PRODUCTION BY HYPOCREA SP Z28 BY SUBMERGED FERMENTATION".CELLULOSE CHEMISTRY AND TECHNOLOGY 52.3-4(2018):259-264.