Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups

doi:10.1016/j.ijbiomac.2017.11.092

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups
	Zhang, Jingjing ; Tan, Wenqiang ; Zhang, Zhenpeng ; Song, Yinping ; Li, Qing ; Dong, Fang ; Guo, Zhanyong
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2018-04
卷号	109 页码:1061-1067
关键词	Antifungal activity Beneficial soil microbes Chitosan derivatives Structure characteristics Urea groups
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2017.11.092
产权排序	[Zhang, Jingjing ; Tan, Wenqiang ; Zhang, Zhenpeng ; Song, Yinping ; Li, Qing ; Dong, Fang ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Zhang, Jingjing ; Tan, Wenqiang ; Zhang, Zhenpeng ; Song, Yinping ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
文献子类	Article
英文摘要	As an abundant and renewable polysaccharide, chitosan has been drawing broad attention due to its natural properties. For the further utilization of chitosan, chemical modification can be applied in improving its water solubility and the bioactivities. In this study, four chitosan derivatives were synthesized by the reaction of chloracetyl chitosan derivative with quaternary ammonium salt (CTCS) and urea groups bearing 4-amino-pyridine, including BCTCS, 2CBCTCS, 3CBCTCS, and 4CBCTCS. The structure characteristics of synthesized products were established based on FT-1R spectroscopy, H-1 NMR, and elemental analysis. Their antifungal activities against Fusarium oxysporum f. sp. niveum, Phomopsis asparagus, Fusarium oxysporum f. sp. cucumebrium Owen, and Botrytis cinerea were estimated by hyphal measurement in vitro. Generally, the inhibition ratio of most products was higher than 80% at 1.0 mg/mL. Their inhibitory activity decreased roughly in the order: 4CBCTCS > 3CBCTCS > 2CBCTCS> BCTCS > CTCS> chitosan, resulted from the different degrees of substitution of the effectively active groups-urea groups. Meanwhile, the effects on beneficial soil microbes, including Bacillus cereus, Bacillus subtilis, and Sinorhizobium saheli LMG7837, of these synthesized chitosan derivatives were evaluated by disk diffusion method. The results showed that these substances do not inhibit the growth of beneficial bacteria and some of them could be employed as green antifungal biomaterials. (C) 2017 Elsevier B.V. All rights reserved.
WOS关键词	FUNCTIONALIZED CHITOSAN ; ANTIBACTERIAL ACTIVITY ; ANTIOXIDANT ACTIVITIES ; QUATERNIZED CHITOSAN ; INULIN DERIVATIVES ; FACILE SYNTHESIS ; IN-SILICO ; AGENTS ; COMPLEXES ; CONJUGATION
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
语种	英语
WOS记录号	WOS:000428099900115
资助机构	National Natural Science Foundation of China [41576156] ; Shandong Province Science and Technology Development Plan [2015GSF121045] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [2015418022-3]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24379]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_污染过程与控制实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Jingjing,Tan, Wenqiang,Zhang, Zhenpeng,et al. Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,109:1061-1067.
APA	Zhang, Jingjing.,Tan, Wenqiang.,Zhang, Zhenpeng.,Song, Yinping.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,109,1061-1067.
MLA	Zhang, Jingjing,et al."Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 109(2018):1061-1067.