High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System

doi:10.1109/TASC.2018.2836999

CORC > 合肥物质科学研究院 > 中国科学院合肥物质科学研究院 > 中科院等离子体物理研究所

	High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System
	Li, Da 2,3; Ren, Yong 1
刊名	IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY
	2018-09-01
卷号	28 期号:6 页码:7
关键词	Gradient magnetic field magnetically targeted drug delivery system (MTDDS) superconducting magnet
ISSN号	1051-8223
DOI	10.1109/TASC.2018.2836999
通讯作者	Ren, Yong(renyong@mail.ustc.edu.cn)
英文摘要	Magnetic nanoparticles (MNPs), which can be transported through the vascular system and concentrated at the specific position of the body under an externalmagnetic field, are attracting increasing attention in tumor treatment. The MNPs should work under a high-gradient magnetic field for generating the enough magnetic forces to overcome the hydrodynamic drag force acting on the nanoparticles from the blood flow. Previous study on magnet-guided drug delivery has focused mainly on the synthesis and surface engineering of MNPs. In this study, the REBa2 Cu3OX [RE = rare earth] (REBCO) magnet, which is composed of three sets of coils, was designed for providing the gradient magnetic field in three perpendicular directions. The magnet system is geometrically compact to allow the mice to lie down. The three gradient magnetic fields and uniform magnetic fields near the magnetic field center can be generated in X-, Y-, and Z-directions, respectively. This paper describes the design and electromagnetic analysis of the superconducting magnet. In addition, the advantages and limitations of our design and future development will be presented.
资助项目	National Natural Science Foundation of China[51406215] ; Anhui Provincial Natural Science Foundation[1408085QE90]
WOS关键词	SILICA NANOPARTICLES ; CANCER
WOS研究方向	Engineering ; Physics
语种	英语
出版者	IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
WOS记录号	WOS:000435202300001
资助机构	National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; 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National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/38141]
专题	合肥物质科学研究院_中科院等离子体物理研究所
通讯作者	Ren, Yong
作者单位	1.Chinese Acad Sci, Inst Plasma Phys, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China 2.Anhui Med Univ, Dept Tradit Chinese Med, Affiliated Hosp 3, Hefei 230061, Anhui, Peoples R China 3.First Peoples Hosp Hefei, Dept Tradit Chinese Med, Hefei 230061, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Li, Da,Ren, Yong. High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System[J]. IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY,2018,28(6):7.
APA	Li, Da,&Ren, Yong.(2018).High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System.IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY,28(6),7.
MLA	Li, Da,et al."High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System".IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY 28.6(2018):7.