Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions

doi:10.1080/00397911.2010.494814

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	Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions
	Lei, Min2 ; Ma, Lei 2; Hu, Lihong 1,2
刊名	SYNTHETIC COMMUNICATIONS
	2011
卷号	41 期号:13 页码:1969-1976
关键词	Aldehydes 1 4-dihydropyridines Hantzsch reaction -keto ester thiamine hydrochloride (VB(1))
ISSN号	0039-7911
DOI	10.1080/00397911.2010.494814
文献子类	Article
英文摘要	[image omitted] An efficient one-pot synthesis of 1,4-dihydropyridines from an aldehyde, -keto ester, and ammonium acetate or formamidine acetate using thiamine hydrochloride (VB1) as the catalyst under solvent-free conditions at ambient temperature is described. All types of aldehydes, including aromatic, aliphatic, and unsaturated aldehydes, give good yields. The catalyst can easily be recovered after completion of the reaction and reused without affecting its activity.
资助项目	Chinese National Science and Technology[2009ZX09301-001] ; Chinese National Science and Technology[2009ZX09102] ; Chinese National High-tech RD Program[2007AA02Z147] ; National Natural Science Foundation of China[90713046] ; National Natural Science Foundation of China[30772638] ; National Natural Science Foundation of China[30925040] ; CAS Foundation[KSCX2-YW-R-179]
WOS关键词	POLYHYDROQUINOLINE DERIVATIVES ; HANTZSCH 1,4-DIHYDROPYRIDINES ; CALCIUM-CHANNEL ; AMBIENT-TEMPERATURE ; ANTAGONISTS ; CONDENSATION
WOS研究方向	Chemistry
语种	英语
出版者	TAYLOR & FRANCIS INC
WOS记录号	WOS:000290409100011
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/278680]
专题	上海中药现代化研究中心
通讯作者	Ma, Lei
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;
推荐引用方式 GB/T 7714	Lei, Min,Ma, Lei,Hu, Lihong. Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions[J]. SYNTHETIC COMMUNICATIONS,2011,41(13):1969-1976.
APA	Lei, Min,Ma, Lei,&Hu, Lihong.(2011).Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions.SYNTHETIC COMMUNICATIONS,41(13),1969-1976.
MLA	Lei, Min,et al."Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions".SYNTHETIC COMMUNICATIONS 41.13(2011):1969-1976.