Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity

doi:10.1016/j.phytochem.2014.07.012

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 上海中药现代化研究中心

	Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity
	Yang, Wen-zhi 2; Hu, Ying 1; Wu, Wan-ying2 ; Ye, Min 1; Guo, De-an2
刊名	PHYTOCHEMISTRY
	2014-10
卷号	106 页码:7-24
关键词	Panax genus Panax ginseng Panax quinquefolius Panax notoginseng Araliaceae Saponins Chemical diversity Subtype classification
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2014.07.012
文献子类	Review
英文摘要	The Panax genus is a crucial source of natural medicines that has benefited human health for a long time. Three valuable medicinal herbs, namely Panax ginseng, Panax quinquefolius, and Panax notoginseng, have received considerable interest due to their extensive application in clinical therapy, healthcare products, and as foods and food additives world-wide. Panax species are known to contain abundant levels of saponins, also dubbed ginsenosides, which refer to a series of dammarane or oleanane type triterpenoid glycosides. These saponins exhibit modulatory effects to the central nervous system and beneficial effects to patients suffering from cardiovascular diseases, and also have anti-diabetic and anti-tumor properties. To the end of 2012, at least 289 saponins were reported from eleven different Panax species. This comprehensive review describes the advances in the phytochemistry of the genus Panax for the period 1963-2012, based on the 134 cited references. The reported saponins can be classified into protopanaxadiol, protopanaxatriol, octillol, oleanolic acid, C17 side-chain varied, and miscellaneous subtypes, according to structural differences in sapogenins. The investigational history of Panax is also reviewed, with special attention being paid to the structural features of the six different subtypes, together with their H-1 and C-13 NMR spectroscopic characteristics which are useful for determining their structures and absolute configuration. (C) 2014 Elsevier Ltd. All rights reserved.
资助项目	Program for New Century Excellent Talents in University from China Ministry of Education[BMU20110269]
WOS关键词	DAMMARANE-TYPE SAPONINS ; KOREAN RED GINSENG ; HEAT-PROCESSED GINSENG ; ORIENTAL PLANT DRUGS ; F H. CHEN ; FLOWER-BUDS ; TRITERPENE SAPONINS ; QUINQUEFOLIUM-L ; CA MEYER ; BIOACTIVE SAPONINS
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000342258600001
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276890]
专题	上海中药现代化研究中心
通讯作者	Ye, Min
作者单位	1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 2.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
推荐引用方式 GB/T 7714	Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,et al. Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity[J]. PHYTOCHEMISTRY,2014,106:7-24.
APA	Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,Ye, Min,&Guo, De-an.(2014).Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity.PHYTOCHEMISTRY,106,7-24.
MLA	Yang, Wen-zhi,et al."Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity".PHYTOCHEMISTRY 106(2014):7-24.