Rh(III)-Catalyzed Addition of Alkenyl C-H Bond to Isocyanates and Intramolecular Cyclization: Direct Synthesis 5-Ylidenepyrrol-2(5H)-ones

doi:10.1021/ol4003674

	Rh(III)-Catalyzed Addition of Alkenyl C-H Bond to Isocyanates and Intramolecular Cyclization: Direct Synthesis 5-Ylidenepyrrol-2(5H)-ones
	Hou, Wei; Zhou, Bing; Yang, Yaxi; Feng, Huijin; Li, Yuanchao
刊名	ORGANIC LETTERS
	2013-04-19
卷号	15 期号:8 页码:1814-1817
ISSN号	1523-7060
DOI	10.1021/ol4003674
文献子类	Article
英文摘要	The rhodium-catalyzed addition of an alkenyl C-H bond to isocyanates via sp(2) C-H bond activation followed by an intramolecular cyclization is described. This atom-economic and catalytic reaction affords a simple and straightforward access to biologically relevant 5-ylidene pyrrol-2(5H)-ones and can be carried out under mild and neutral conditions in the absence of any additives and environmentally hazardous waste production.
WOS关键词	CATALYZED CONJUGATE ADDITION ; OXIDATIVE ORTHO-ACYLATION ; RHODIUM(III)-CATALYZED SYNTHESIS ; DIRECT FUNCTIONALIZATION ; REGIOSELECTIVE SYNTHESIS ; ACID-DERIVATIVES ; INTERNAL ALKYNES ; MILD CONDITIONS ; ACTIVATION ; ALDEHYDES
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000318001400007
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277649]
专题	药物化学研究室
通讯作者	Zhou, Bing
作者单位	Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Hou, Wei,Zhou, Bing,Yang, Yaxi,et al. Rh(III)-Catalyzed Addition of Alkenyl C-H Bond to Isocyanates and Intramolecular Cyclization: Direct Synthesis 5-Ylidenepyrrol-2(5H)-ones[J]. ORGANIC LETTERS,2013,15(8):1814-1817.
APA	Hou, Wei,Zhou, Bing,Yang, Yaxi,Feng, Huijin,&Li, Yuanchao.(2013).Rh(III)-Catalyzed Addition of Alkenyl C-H Bond to Isocyanates and Intramolecular Cyclization: Direct Synthesis 5-Ylidenepyrrol-2(5H)-ones.ORGANIC LETTERS,15(8),1814-1817.
MLA	Hou, Wei,et al."Rh(III)-Catalyzed Addition of Alkenyl C-H Bond to Isocyanates and Intramolecular Cyclization: Direct Synthesis 5-Ylidenepyrrol-2(5H)-ones".ORGANIC LETTERS 15.8(2013):1814-1817.