Synthesis and Characterization of 3, 4, 5-triphenolbenzoylsalicylaldehyde Hydrazone and its Rare Earth Metal Complexes with Antitumor Activities

doi:10.1080/15533170802525795

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Synthesis and Characterization of 3, 4, 5-triphenolbenzoylsalicylaldehyde Hydrazone and its Rare Earth Metal Complexes with Antitumor Activities
	Zhang, Ling 2,4; Zhang, Bao-Hua 2; Zhu, Da-Yuan 1,3
刊名	SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY
	2008
卷号	38 期号:10 页码:742-745
关键词	antitumor activity complexes hydrazone rare earth metals synthesis
ISSN号	1553-3174
DOI	10.1080/15533170802525795
文献子类	Article
英文摘要	A new gallic acid derivative, 3, 4, 5-triphenolbenzoylsalicylaldehyde hydrazone (HL), and its four rare earth metal complexes, [LnL (OAc)2] H2O (Ln = La3 +, Sm3 +, Tb3 +, Dy3 +), have been synthesized and characterized on the basis of elemental analyses, molar conductivity, IR and 1H NMR spectra. The antitumor activities against HL-60 and A - 549 cell lines of the prepared compounds have also been evaluated. The results indicate that the antitumor activity against the human leukemia cell lineHL-60 than the ligand HL, and the antitumor activity of the ligand is largely changed by the formation of the complexes.
资助项目	Leading Academic Discipline Project of Shanghai Municipal Education Commission[530109] ; Research Award Fund for Outstanding Young Teachers in Shanghai Higher Education Institutions[17021]
WOS关键词	COORDINATION COMPOUNDS ; TRANSITION-METALS ; DERIVATIVES
WOS研究方向	Chemistry ; Science & Technology - Other Topics
语种	英语
出版者	TAYLOR & FRANCIS INC
WOS记录号	WOS:000261674600003
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273086]
专题	天然药物化学研究室
通讯作者	Zhang, Ling
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.Shanghai Univ, Coll Environm & Chem Engn, Shanghai, Peoples R China; 3.Shanghai Inst Mat Medica, Chinese Acad Sci, Shanghai, Peoples R China; 4.Shanghai Univ, Coll Environm & Chem Engn, Dept Chem Engn & Technol, Shanghai 201800, Peoples R China;
推荐引用方式 GB/T 7714	Zhang, Ling,Zhang, Bao-Hua,Zhu, Da-Yuan. Synthesis and Characterization of 3, 4, 5-triphenolbenzoylsalicylaldehyde Hydrazone and its Rare Earth Metal Complexes with Antitumor Activities[J]. SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY,2008,38(10):742-745.
APA	Zhang, Ling,Zhang, Bao-Hua,&Zhu, Da-Yuan.(2008).Synthesis and Characterization of 3, 4, 5-triphenolbenzoylsalicylaldehyde Hydrazone and its Rare Earth Metal Complexes with Antitumor Activities.SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY,38(10),742-745.
MLA	Zhang, Ling,et al."Synthesis and Characterization of 3, 4, 5-triphenolbenzoylsalicylaldehyde Hydrazone and its Rare Earth Metal Complexes with Antitumor Activities".SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY 38.10(2008):742-745.