Pd-Catalyzed Acetoxylation of gamma-C(sp(3))-H Bonds of Amines Directed by a Removable Bts-Protecting Group

doi:10.1021/acs.joc.7b02995

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	Pd-Catalyzed Acetoxylation of gamma-C(sp(3))-H Bonds of Amines Directed by a Removable Bts-Protecting Group
	Zheng, Yong; Song, Weibin; Zhu, Yefu; Wei, Bole; Xuan, Lijiang
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2018-02-16
卷号	83 期号:4 页码:2448-2454
ISSN号	0022-3263
DOI	10.1021/acs.joc.7b02995
文献子类	Article
英文摘要	Pd-catalyzed acetoxylation of gamma-C(sp(3))-H bonds directed by Bts-protected amines using inexpensive PhI(OAc)(2) as oxidant is reported. The Bts-protecting group is easily introduced and removed under mild conditions. This protocol provides an important strategy for the construction of gamma-hydroxyl amine derivatives.
资助项目	National Natural Science Foundation of China[81602995]
WOS关键词	C-H ACTIVATION ; NATIVE CHEMICAL LIGATION ; CARBON-HYDROGEN BONDS ; EFFICIENT SYNTHESES ; ACID-DERIVATIVES ; FUNCTIONALIZATION ; C(SP(3))-H ; C(SP(2))-H ; INHIBITOR ; AUXILIARY
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000427094200081
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279897]
专题	上海中药现代化研究中心中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Xuan, Lijiang
作者单位	Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Yong,Song, Weibin,Zhu, Yefu,et al. Pd-Catalyzed Acetoxylation of gamma-C(sp(3))-H Bonds of Amines Directed by a Removable Bts-Protecting Group[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(4):2448-2454.
APA	Zheng, Yong,Song, Weibin,Zhu, Yefu,Wei, Bole,&Xuan, Lijiang.(2018).Pd-Catalyzed Acetoxylation of gamma-C(sp(3))-H Bonds of Amines Directed by a Removable Bts-Protecting Group.JOURNAL OF ORGANIC CHEMISTRY,83(4),2448-2454.
MLA	Zheng, Yong,et al."Pd-Catalyzed Acetoxylation of gamma-C(sp(3))-H Bonds of Amines Directed by a Removable Bts-Protecting Group".JOURNAL OF ORGANIC CHEMISTRY 83.4(2018):2448-2454.