Study on the reaction for synthesis of 3beta, 21-dihydroxypregn- 5-en-20-one-21-methylether

	Study on the reaction for synthesis of 3beta, 21-dihydroxypregn- 5-en-20-one-21-methylether
	LUO Lei 2; CHEN Guorong 2; FENG Huifin 1; WANG Youfu 3; LI Yuanchao 1
刊名	Chemical Reagents
	2008
卷号	30 期号:9 页码:702-704
关键词	Lewis acid （diaceoxyiodo）benzene 3beta-hydroxypregn-5-en-20-one oxidation
ISSN号	0258-3283
其他题名	3beta,21-二羟基孕甾-Delta~5-烯-20-酮-21-甲醚的合成反应研究
文献子类	Article
英文摘要	In a methanol solution, 3beta-hydmxypregn-5-en-20-one （1） ,catalyzed by lewis acid, could be oxidized directly to 3beta, 21-dihydroxypregn-5-en-20-one-21-methylether under the effect of （diaceoxyiodo）benzene [PhI（OAc）_2] in high yield and good selectivity. Then the influences of different Lewis acids and different solvents on the yield of reaction product were investigated, and influences of the Lewis acid equivalent on the reaction time were discussed.
WOS研究方向	Chemistry (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:3394699
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/268074]
专题	信息中心药理学第二研究室药理学第一研究室
作者单位	1.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; 2.School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.; 3.Zhejiang Shenzhou Pharmaceutical Co., Ltd, Xianju, 317300.
推荐引用方式 GB/T 7714	LUO Lei,CHEN Guorong,FENG Huifin,et al. Study on the reaction for synthesis of 3beta, 21-dihydroxypregn- 5-en-20-one-21-methylether[J]. Chemical Reagents,2008,30(9):702-704.
APA	LUO Lei,CHEN Guorong,FENG Huifin,WANG Youfu,&LI Yuanchao.(2008).Study on the reaction for synthesis of 3beta, 21-dihydroxypregn- 5-en-20-one-21-methylether.Chemical Reagents,30(9),702-704.
MLA	LUO Lei,et al."Study on the reaction for synthesis of 3beta, 21-dihydroxypregn- 5-en-20-one-21-methylether".Chemical Reagents 30.9(2008):702-704.