Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc

doi:10.1021/acs.jnatprod.5b00520

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc
	Zhang, Panpan 1,2,3; Tang, Chunping1,2,4,5 ; Yao, Sheng1,2,4,5 ; Ke, Changqiang1,2,4,5 ; Lin, Ge 4,5,6; Hua, Hui-Ming 3; Ye, Yang1,2,4,5,7
刊名	JOURNAL OF NATURAL PRODUCTS
	2016-01
卷号	79 期号:1 页码:24-29
ISSN号	0163-3864
DOI	10.1021/acs.jnatprod.5b00520
文献子类	Article
英文摘要	Ten new cassane-type diterpenoids, caesalbonducins DF (13), 6-deacetoxybonducellpin B (4), 3-acetoxy-alpha-caesalpin (5), 2(3)-en-alpha-caesalpin (6), 1 alpha-hydroxycaesalpinin J (7), 1 alpha-hydroxy-6-decaetoxysalpinin J (8), 6 alpha-hydroxycaesall M (9), and 6 alpha-hydroxy-14(17)-dehydrocaesalpin F (10), along with eight known compounds (1118), were isolated from the pericarps of Caesalpinia bonduc. Compounds 13 and 11 are methyl-migrated cassane-type diterpenoids with a 19(4 -> 3)-cassane skeleton. The structures of 110 were elucidated on the basis of 1D and 2D NMR methods and other spectroscopic analysis. The neuroprotective effects of the isolated compounds were evaluated.
资助项目	National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program"[2012ZX09301001-001] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program"[2015ZX09103002] ; National Natural Science Funds of China[81302657] ; National Natural Science Funds of China[81573305] ; National Natural Science Funds of China[81473112] ; Ministry of Science and Technology[2010DFA30980] ; Chinese Academy of Sciences[KSZD-EW-Z-004-01] ; Shanghai Commission of Science and Technology[11DZ1970700] ; Shanghai Commission of Science and Technology[12JC1410300]
WOS关键词	SEED KERNELS ; CRISTA ; FURANODITERPENES
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000368755000004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276254]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Hua, Hui-Ming; Ye, Yang
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Nat Prod Chem Dept, 555 Zu Chong Zhi Rd,Zhangjiang Hi Tech Pk, Shanghai 201203, Peoples R China; 3.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Joint Res Lab Promoting Globalizat Tradit Chines, Hong Kong, Hong Kong, Peoples R China; 5.Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China; 6.Chinese Univ Hong Kong, Fac Med, Sch Biomed Sci, Hong Kong, Hong Kong, Peoples R China; 7.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Panpan,Tang, Chunping,Yao, Sheng,et al. Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc[J]. JOURNAL OF NATURAL PRODUCTS,2016,79(1):24-29.
APA	Zhang, Panpan.,Tang, Chunping.,Yao, Sheng.,Ke, Changqiang.,Lin, Ge.,...&Ye, Yang.(2016).Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc.JOURNAL OF NATURAL PRODUCTS,79(1),24-29.
MLA	Zhang, Panpan,et al."Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc".JOURNAL OF NATURAL PRODUCTS 79.1(2016):24-29.