Synthesis and insulin-sensitizing activity of a series of 2-benzyl-1,3-dicarbonyl derivatives

	Synthesis and insulin-sensitizing activity of a series of 2-benzyl-1,3-dicarbonyl derivatives
	Tang, L; Leng, Y; Wang, HQ; Feng, Y; Yang, YS; Ji, RY
刊名	CHINESE JOURNAL OF CHEMISTRY
	2003-04
卷号	21 期号:4 页码:365-368
关键词	insulin-sensitizing activity 3T3-L1 cells type 2 diabetes
ISSN号	1001-604X
文献子类	Article
英文摘要	A series of 2-benzyl-1,3-dicabonyl derivatives was synthesized. Their insulin-sensitizing activity was evaluated in 3T3-L1 preadipocyte cells. Compounds 3, 26 and 27 were found to possess strong insulin-sensitizing activity in vitro and were selected for further hypoglycemic evaluation in vivo.
WOS关键词	AGENTS
WOS研究方向	Chemistry
语种	英语
出版者	SCIENCE CHINA PRESS
WOS记录号	WOS:000186154800001
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/274248]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Yang, YS
作者单位	Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China
推荐引用方式 GB/T 7714	Tang, L,Leng, Y,Wang, HQ,et al. Synthesis and insulin-sensitizing activity of a series of 2-benzyl-1,3-dicarbonyl derivatives[J]. CHINESE JOURNAL OF CHEMISTRY,2003,21(4):365-368.
APA	Tang, L,Leng, Y,Wang, HQ,Feng, Y,Yang, YS,&Ji, RY.(2003).Synthesis and insulin-sensitizing activity of a series of 2-benzyl-1,3-dicarbonyl derivatives.CHINESE JOURNAL OF CHEMISTRY,21(4),365-368.
MLA	Tang, L,et al."Synthesis and insulin-sensitizing activity of a series of 2-benzyl-1,3-dicarbonyl derivatives".CHINESE JOURNAL OF CHEMISTRY 21.4(2003):365-368.