Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities
Tang, Chun-Ping1; Chen, Tong1; Velten, Robert2; Jeschke, Peter2; Ebbinghaus-Kintscher, Ulrich3; Geibel, Sven3; Ye, Yang1
刊名JOURNAL OF NATURAL PRODUCTS
2008-01
卷号71期号:1页码:112-116
ISSN号0163-3864
DOI10.1021/np070427k
文献子类Article
英文摘要Five new alkaloids, 6 beta-hydroxystemofoline (1), 16-hydroxystemofoline (2), neostemofoline (3), protostemodiol (4), and 13-demethoxy-11(S*),12(R*)-dihydroprotostemonine (5), along with 10 known alkaloids, were isolated from stems and leaves of Stemona japonica. Their structures were elucidated by 1D and 2D NMR and other spectroscopic studies. The insecticidal activity of the agonist 16-hydroxystemofoline (2) and antagonist 13-demethoxy-11(S*),l2(R*)-dihydroprotostemonine (5) was demonstrated by electrophysiological in vitro tests on the insect nicotinic acetylcholine receptor and by in vivo screenings against relevant agricultural insect pests.
WOS关键词TUBEROSA ; ROOTS
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
出版者AMER CHEMICAL SOC
WOS记录号WOS:000252629400024
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/273065]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Ye, Yang
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
2.Bayer CropSci AG, Res Insecticides, Chem Insecticides, D-40789 Monheim, Germany;
3.Bayer CropSci AG, Res Insecticides, Biol Insecticides, D-40789 Monheim, Germany
推荐引用方式
GB/T 7714
Tang, Chun-Ping,Chen, Tong,Velten, Robert,et al. Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(1):112-116.
APA Tang, Chun-Ping.,Chen, Tong.,Velten, Robert.,Jeschke, Peter.,Ebbinghaus-Kintscher, Ulrich.,...&Ye, Yang.(2008).Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities.JOURNAL OF NATURAL PRODUCTS,71(1),112-116.
MLA Tang, Chun-Ping,et al."Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities".JOURNAL OF NATURAL PRODUCTS 71.1(2008):112-116.
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