New triterpene glucosides from the roots of Rosa laevigata michx

doi:10.3390/molecules13092229

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	New triterpene glucosides from the roots of Rosa laevigata michx
	Yuan, Jing-Quan 1,2; Yang, Xin-Zhou 2; Miao, Jian-Hua 1; Tang, Chun-Ping2 ; Ke, Chang-Qiang2 ; Zhang, Ji-Bao 2; Ma, Xiao-Jun 1,3,4; Ye, Yang2
刊名	MOLECULES
	2008-09
卷号	13 期号:9 页码:2229-2237
关键词	ursane-type triterpene glucosides Rosa laevigata antifungal activity
ISSN号	1420-3049
DOI	10.3390/molecules13092229
文献子类	Article
英文摘要	Two new ursane-type triterpene glucosides, 2 alpha,3 alpha,24-trihydroxyurs-12,18-dien-28-oic acid beta-D-glucopyranosyl ester (1) and 2 alpha,3 alpha,23-trihydroxyurs-12,19(29)-dien-28-oic acid beta-D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2 alpha,3 alpha,19 alpha-trihydroxyurs-12-en-28-oic acid beta-D-glucopyranosyl ester (3), 2 alpha,3 alpha,19 alpha-trihydroxyurs-12-en-28-oic acid beta-D-glucopyranosyl ester (4) and 2 alpha,3 alpha,19 alpha, 23-tetrahydroxyurs-12-en-28-oic acid beta-D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and 5 exhibited modest in vitro antifungal activities against Candida albicans and C. krusei.
资助项目	Ministry of Science and Technology[2004CB518902] ; Science and Technology Commission of Shanghai Municipality[036505003]
WOS关键词	COMBRETUM-QUADRANGULARE ; SEEDS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MOLECULAR DIVERSITY PRESERVATION INT
WOS记录号	WOS:000259735800014
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272826]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Ma, Xiao-Jun
作者单位	1.Guangxi Inst Med Plant, Nanning 530023, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Peking Union Med Coll, Beijing 100094, Peoples R China; 4.Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Jing-Quan,Yang, Xin-Zhou,Miao, Jian-Hua,et al. New triterpene glucosides from the roots of Rosa laevigata michx[J]. MOLECULES,2008,13(9):2229-2237.
APA	Yuan, Jing-Quan.,Yang, Xin-Zhou.,Miao, Jian-Hua.,Tang, Chun-Ping.,Ke, Chang-Qiang.,...&Ye, Yang.(2008).New triterpene glucosides from the roots of Rosa laevigata michx.MOLECULES,13(9),2229-2237.
MLA	Yuan, Jing-Quan,et al."New triterpene glucosides from the roots of Rosa laevigata michx".MOLECULES 13.9(2008):2229-2237.