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	Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan
	Wu, Zheng-Feng2; Bao, Han2; Zhou, Fa-Yang2; Liu, Jing-Xin2; Meng, Fan-Cheng2; Feng, Lu1,3; Lu, Jin-Jian2; Zhang, Qing-Wen2; Ye, Yang1,3; Lin, Li-Gen2
刊名	CHINESE CHEMICAL LETTERS
	2017-08
卷号	28期号:8页码:1711-1715
关键词	Caesalpinia sappan Cassane diterpenoid Phanginin Caesalsappanin Cytotoxicity
ISSN号	1001-8417
DOI	10.1016/j.cclet.2017.04.023
文献子类	Article
英文摘要	Phytochemical investigation on the seeds of Caesalpinia sappan led to the isolation of five new cassane-type diterpenoids, named 11-oxo-phanginin A (1), caesalsappanins O-Q (2-4) and phanginin U (5), together with five known compounds. The structures of the new compounds were elucidated by extensive analysis of mass spectrometric and 1D and 2D NMR spectroscopic data. All the new compounds showed moderate cytotoxic effects on human breast cancer MCF-7 and human colon cancer HCT116 cell lines. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
资助项目	Science and Technology Development Fund, Macao S.A.R[FDCT 120/2013/A3] ; Research Fund of University of Macau[MYRG2014-00020-ICMS-QRCM] ; Research Fund of University of Macau[MYRG2015-00153-ICMS-QRCM]
WOS研究方向	Chemistry
语种	英语
CSCD记录号	CSCD:6037489
出版者	ELSEVIER SCIENCE INC
WOS记录号	WOS:000407411600014
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272544]
专题	天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室
通讯作者	Lin, Li-Gen
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Nat Prod Chem Dept, Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China 2.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China;
推荐引用方式 GB/T 7714	Wu, Zheng-Feng,Bao, Han,Zhou, Fa-Yang,et al. Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan[J]. CHINESE CHEMICAL LETTERS,2017,28(8):1711-1715.
APA	Wu, Zheng-Feng.,Bao, Han.,Zhou, Fa-Yang.,Liu, Jing-Xin.,Meng, Fan-Cheng.,...&Lin, Li-Gen.(2017).Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan.CHINESE CHEMICAL LETTERS,28(8),1711-1715.
MLA	Wu, Zheng-Feng,et al."Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan".CHINESE CHEMICAL LETTERS 28.8(2017):1711-1715.

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