Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata

doi:10.1016/j.tet.2006.03.108

	Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata
	Pu, Jian-Xin ; Li, Rong-Tao ; Xiao, Wei-Lie ; Gong, Ning-Bo ; Huang, Sheng-Xiong ; Lu, Yang ; Zheng, Qi-Tai ; Lou, Li-Guang; Sun, Han-Dong
刊名	TETRAHEDRON
	2006-06-19
卷号	62 期号:25 页码:6073-6081
关键词	longipedlactones A-I Kadsura longipedunculata structure elucidation biogenesis bioactivity
ISSN号	0040-4020
DOI	10.1016/j.tet.2006.03.108
文献子类	Article
英文摘要	Nine novel triterpene dilactones with an unprecedented rearranged pentacyclic skeleton, longipedlactones A-I (1-9), have been isolated from the leaves and stems of Kadsura longipedunculata Finer et Gagnep (Schisandraceae). Their structures were determined on the basis of comprehensive spectroscopic analysis and single-crystal X-ray structure determination. A biogenetic pathway for longipedlactone A (1) was also proposed. Compounds 1-3, 6, and 8 showed significant cytotoxicity against A549, with HT-29 and K562 cell lines having IC50 values of 0.84-11.38 mu M in vitro. (c) 2006 Elsevier Ltd. All rights reserved.
WOS关键词	LIGNANS
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000238171600029
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273564]
专题	中国科学院上海药物研究所
通讯作者	Sun, Han-Dong
作者单位	1.Peking Union Med Coll, Beijing 100050, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Yunnan, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 200032, Peoples R China
推荐引用方式 GB/T 7714	Pu, Jian-Xin,Li, Rong-Tao,Xiao, Wei-Lie,et al. Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata[J]. TETRAHEDRON,2006,62(25):6073-6081.
APA	Pu, Jian-Xin.,Li, Rong-Tao.,Xiao, Wei-Lie.,Gong, Ning-Bo.,Huang, Sheng-Xiong.,...&Sun, Han-Dong.(2006).Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata.TETRAHEDRON,62(25),6073-6081.
MLA	Pu, Jian-Xin,et al."Longipedlactones A-I, nine novel triterpene dilactones possessing a unique skeleton from Kadsura longipedunculata".TETRAHEDRON 62.25(2006):6073-6081.