Transplantation model of human lung oat cell carcinoma in nude mice

	Transplantation model of human lung oat cell carcinoma in nude mice
	Zhang, S Y; Dai, Z Q; Shu, Y H; Zhang, J L; Xu, B; Lin, Z Q; Wu, S F; Liu, Y F; Xu, L Z
	1987-09
卷号	9
期号	5
页码	333-5, 20
英文摘要	A human lung oat cell carcinoma from a surgical specimen was successfully transplanted into nude mice and has been maintained for over four years through 14 passages. This transplanted tumor had a long latent period of more than one month, slowly growing in the initial inoculation and the following passages. The interval between two passages was about four months. 5 months after the inoculation, the transplanted tumor in nude mice grew to 2 cm in diameter. It was demonstrated that the transplanted tumor possessed the human isoenzyme pattern and human chromosome karyotype. The original human tumor and its transplanted counterparts in the nude mice were strikingly similar by histopathology. Besides, specific neuro-secretory granules in cytoplasm of the transplanted tumor were observed under transmission electron microscope.
会议录	Zhonghua zhong liu za zhi [Chinese journal of oncology]
文献子类	Meeting Abstract;Article
语种	中文
内容类型	会议论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266926]
专题	中国科学院上海药物研究所
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Sciences
推荐引用方式 GB/T 7714	Zhang, S Y,Dai, Z Q,Shu, Y H,et al. Transplantation model of human lung oat cell carcinoma in nude mice[C]. 见:.