Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics

doi:10.1002/smll.201901834

	Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics
	Huo, Minfeng; Wang, Liying; Zhang, Haixian; Zhang, Linlin; Chen, Yu; Shi, Jianlin
刊名	SMALL
	2019-08-01
卷号	15 期号:31
关键词	antibacterial anti-infection peroxidase-like performance photothermal single-atom catalysts
ISSN号	1613-6810
DOI	10.1002/smll.201901834
文献子类	Article
英文摘要	Bacterial infection caused by pathogenic bacteria has long been an intractable issue that threatens human health. Herein, the fact that nanocatalysts with single iron atoms anchored in nitrogen-doped amorphous carbon (SAF NCs) can effectively induce peroxidase-like activities in the presence of H2O2, generating abundant hydroxyl radicals for highly effective bacterial elimination (e.g., Escherichia coli and Staphylococcus aureus), is reported. In combination with the intrinsic photothermal performance of the nanocatalysts, noticeable bacterial-killing effects are extensively investigated. Especially, the antibacterial mechanism of critical cell membrane destruction induced by SAF NCs is unveiled. Based on the bactericidal properties of SAF NCs, in vivo bacterial infections propagated at wounds by E. coli and S. aureus pathogens can be effectively eradicated, resulting in better wound healing. Collectively, the present study highlights the highly efficient in vitro antibacterial and in vivo anti-infection performances by the single-iron-atom-containing nanocatalysts.
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	WILEY-V C H VERLAG GMBH
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/26935]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Huo, Minfeng,Wang, Liying,Zhang, Haixian,et al. Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics[J]. SMALL,2019,15(31).
APA	Huo, Minfeng,Wang, Liying,Zhang, Haixian,Zhang, Linlin,Chen, Yu,&Shi, Jianlin.(2019).Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics.SMALL,15(31).
MLA	Huo, Minfeng,et al."Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics".SMALL 15.31(2019).