Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration

doi:10.1039/c9nr02955a

	Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration
	Liu, Yaqin; Yu, Qingqing; Chang, Jiang; Wu, Chengtie
刊名	NANOSCALE
	2019-08-07
卷号	11 期号:29 页码:13678
ISSN号	2040-3364
DOI	10.1039/c9nr02955a
文献子类	Review
英文摘要	Nanobiomaterials have attracted tremendous attention in the biomedical field. Especially in the past few years, a large number of low dimensional nanobiomaterials, including 0D nanostructures, 1D nanotubes and 2D nanosheets, were employed for tumor therapy due to their optically triggered tumor therapy effects and drug loading capacities. However, these low dimensional nanobiomaterials cannot support cell adhesion and possess poor tissue regeneration ability, thus they are not suitable for application in regenerative medicine. Three dimensional (3D) nanofiber scaffolds have attracted extensive attention in tissue regeneration, including bone, skin, nerve and cardiac tissues, due to their similar extracellular matrix structures. Additionally, many 3D scaffolds displayed bone and cartilage regeneration abilities. Therefore, to obtain materials with both tumor therapy and tissue regeneration abilities, it is meaningful and necessary to develop 3D nanobiomaterials with multifunctions. In this review, we systematically review the research progress of nanobiomaterials with varied dimensional structures including 0D, 1D, 2D and 3D, as well as evolutional functions from single tumor therapy to simultaneous tumor therapy and tissue regeneration. This review may pave the way for developing an interdisciplinary research of nanobiomaterials in combination of tumor therapy and regenerative medicine.
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	ROYAL SOC CHEMISTRY
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/26916]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Liu, Yaqin,Yu, Qingqing,Chang, Jiang,et al. Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration[J]. NANOSCALE,2019,11(29):13678.
APA	Liu, Yaqin,Yu, Qingqing,Chang, Jiang,&Wu, Chengtie.(2019).Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration.NANOSCALE,11(29),13678.
MLA	Liu, Yaqin,et al."Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration".NANOSCALE 11.29(2019):13678.