Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine

doi:10.1002/adma.201903013

	Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine
	Lin, Han; Qiu, Wujie; Liu, Jianjun; Yu, Luodan; Gao, Shanshan; Yao, Heliang; Chen, Yu; Shi, Jianlin
刊名	ADVANCED MATERIALS
	2019-09-01
卷号	31 期号:37
关键词	2D topology biodegradation nanomedicine silicene wet-chemical exfoliation
ISSN号	0935-9648
DOI	10.1002/adma.201903013
文献子类	Article
英文摘要	Silicon-based biomaterials play an indispensable role in biomedical engineering; however, due to the lack of intrinsic functionalities of silicon, the applications of silicon-based nanomaterials are largely limited to only serving as carriers for drug delivery systems. Meanwhile, the intrinsically poor biodegradation nature for silicon-based biomaterials as typical inorganic materials also impedes their further in vivo biomedical use and clinical translation. Herein, by the rational design and wet chemical exfoliation synthesis of the 2D silicene nanosheets, traditional 0D nanoparticulate nanosystems are transformed into 2D material systems, silicene nanosheets (SNSs), which feature an intriguing physiochemical nature for photo-triggered therapeutics and diagnostic imaging and greatly favorable biological effects of biocompatibility and biodegradation. In combination with DFT-based molecular dynamics (MD) calculations, the underlying mechanism of silicene interactions with bio-milieu and its degradation behavior are probed under specific simulated physiological conditions. This work introduces a new form of silicon-based biomaterials with 2D structure featuring biodegradability, biocompatibility, and multifunctionality for theranostic nanomedicine, which is expected to promise high clinical potentials.
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
出版者	WILEY-V C H VERLAG GMBH
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/26867]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Lin, Han,Qiu, Wujie,Liu, Jianjun,et al. Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine[J]. ADVANCED MATERIALS,2019,31(37).
APA	Lin, Han.,Qiu, Wujie.,Liu, Jianjun.,Yu, Luodan.,Gao, Shanshan.,...&Shi, Jianlin.(2019).Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine.ADVANCED MATERIALS,31(37).
MLA	Lin, Han,et al."Silicene: Wet-Chemical Exfoliation Synthesis and Biodegradable Tumor Nanomedicine".ADVANCED MATERIALS 31.37(2019).