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	Chemical constituents from plant endophytic fungus Alternaria alternata
	Wang, Ju-Tao3,4; Ma, Zong-Hui3; Wang, Guo-Kai3,4; Xu, Feng-Qing3,4; Yu, Yang1,2; Wang, Gang3,4; Peng, Dai-Yin3,4; Liu, Jin-Song3,4
刊名	NATURAL PRODUCT RESEARCH
	2019-07-13
页码	8
关键词	Alternaria alternata Paeonia lactiflora benzo-alpha-pyrone derivatives cytotoxic activity
ISSN号	1478-6419
DOI	10.1080/14786419.2019.1639699
通讯作者	Peng, Dai-Yin(pengdy@ahtcm.edu.cn) ; Liu, Jin-Song(jinsongliu@ahtcm.edu.cn)
英文摘要	Five new natural compounds (1-5) along with four known ones, involving dibenzo-alpha-pyrone derivatives, a benzo-gamma-pyrone derivative and an amide-type compound were obtained from Alternaria alternata, an endophyte isolated from Paeonia lactiflora. The structures of these isolates were elucidated by intensive analysis of spectroscopic data including NMR, HRMS (ESI and EI), UV and IR spectra. Compounds (1-4) were evaluated for their cytotoxicities against five selected human tumourtumour cell lines (A-549, MDA-MB-231, MCF-7, KB and KB-VIN), and compound 3 exhibited activities against MDA-MB-231and MCF-7 with IC50 values of 20.1 mu M and 32.2 mu M. [GRAPHICS] .
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000478316400001
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/68202]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Peng, Dai-Yin; Liu, Jin-Song
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Anhui Univ Chinese Med, Sch Pharm, Anhui Key Lab Modern Chinese Mat Med, Hefei, Anhui, Peoples R China 4.Synerget Innovat Ctr Anhui Authent Chinese Med Qu, Hefei, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Wang, Ju-Tao,Ma, Zong-Hui,Wang, Guo-Kai,et al. Chemical constituents from plant endophytic fungus Alternaria alternata[J]. NATURAL PRODUCT RESEARCH,2019:8.
APA	Wang, Ju-Tao.,Ma, Zong-Hui.,Wang, Guo-Kai.,Xu, Feng-Qing.,Yu, Yang.,...&Liu, Jin-Song.(2019).Chemical constituents from plant endophytic fungus Alternaria alternata.NATURAL PRODUCT RESEARCH,8.
MLA	Wang, Ju-Tao,et al."Chemical constituents from plant endophytic fungus Alternaria alternata".NATURAL PRODUCT RESEARCH (2019):8.

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