Total Synthesis of (-)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart

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	Total Synthesis of (-)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart
	Deng J(邓军) ; Zhu B(朱波) ; Lu ZY(鲁照永) ; Yu HX(于海昕) ; Li A(李昂)
刊名	J. Am. Chem. Soc.
	2012
卷号	134 期号:2 页码:920-923
ISSN号	0002-7863
其他题名	(?)-Fusarisetin A的全合成及其绝对构型的更正
通讯作者	李昂
英文摘要	The first total synthesis of (-)-fusarisetin A, the enantiomer of naturally occurring acinar morphogenesis inhibitor (+)-fusarisetin A, was accomplished in 13 steps, leading to the reassignment of the absolute configuration of the natural product. The synthesis featured a Lewis acid-promoted intramolecular Diets-Alder reaction, a Pd-catalyzed O -> C allylic rearrangement, a chemoselective Wacker oxidation, and a Dieckmann condensation/hemiketalization cascade.
学科主题	天然产物有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ja211444m
语种	英语
WOS记录号	WOS:000301084300046
公开日期	2013-08-29
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28613]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Deng J,Zhu B,Lu ZY,et al. Total Synthesis of (-)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart[J]. J. Am. Chem. Soc.,2012,134(2):920-923.
APA	邓军,朱波,鲁照永,于海昕,&李昂.(2012).Total Synthesis of (-)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart.J. Am. Chem. Soc.,134(2),920-923.
MLA	邓军,et al."Total Synthesis of (-)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart".J. Am. Chem. Soc. 134.2(2012):920-923.