Recent development of portable imaging platforms for cell-based assays

doi:10.1016/j.bios.2018.10.024

CORC > 合肥物质科学研究院 > 中国科学院合肥物质科学研究院 > 应用技术研究所

	Recent development of portable imaging platforms for cell-based assays
	Yang, Ke 1,2; Wu, Jiandong 2; Santos, Susy 3; Liu, Yong 1; Zhu, Ling 1; Lin, Francis 2,4,5,6
刊名	BIOSENSORS & BIOELECTRONICS
	2019-01-15
卷号	124 页码:150-160
关键词	Portable imaging platform Cell-based assays Microfluidic device Point-of-care diagnosis
ISSN号	0956-5663
DOI	10.1016/j.bios.2018.10.024
通讯作者	Lin, Francis(flin@physics.umanitoba.ca)
英文摘要	Cell-based assays including both cell identification assays and cell functional assays are broadly used in life science research and for medical applications. Traditionally, cell-based assays are performed in professional laboratories. Although such an approach is reliable, it significantly limits the accessibility of cell-based assays by many researchers without specialized cell imaging facilities and does not permit on-site use at most clinics. Over recent years, growing efforts have been made to overcome this limitation by developing various portable cell imaging platforms. Herein, we provide a timely review on the recent development of portable imaging systems and their biomedical applications. We describe the respective applications of three main classes of portable imaging technologies including miniaturized microscope, lens-free imaging device and smartphone-based microscope for cell-based assays. We conclude by discussing our views on the opportunities, problems and future directions of this emerging field.
资助项目	National Natural Science Foundation of China[31800713] ; Hefei Institute of Physical Science, China[YZJJ2018QN22] ; Key Research and Development Program of Anhui Province of China[1804a09020051] ; Science and Technology Major Program of Anhui Province of China[16030801123] ; National Science and Engineering Research Council of Canada ; Canadian Institutes of Health Research
WOS关键词	FIELD-OF-VIEW ; WIDE-FIELD ; MINI-MICROSCOPE ; IN-VITRO ; CHIP ; CULTURE ; SYSTEM ; POINT ; TECHNOLOGIES ; BIOSENSOR
WOS研究方向	Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
语种	英语
出版者	ELSEVIER ADVANCED TECHNOLOGY
WOS记录号	WOS:000451935500019
资助机构	National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Hefei Institute of Physical Science, China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Key Research and Development Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; Science and Technology Major Program of Anhui Province of China ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; National Science and Engineering Research Council of Canada ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/40614]
专题	合肥物质科学研究院_应用技术研究所
通讯作者	Lin, Francis
作者单位	1.Chinese Acad Sci, Inst Appl Technol, Hefei Inst Phys Sci, Hefei, Anhui, Peoples R China 2.Univ Manitoba, Dept Phys & Astron, Winnipeg, MB, Canada 3.Victoria Gen Hosp & River Hts Ft Gamy Commuity Ar, Winnipeg, MB, Canada 4.Univ Manitoba, Dept Biosyst Engn, Winnipeg, MB, Canada 5.Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada 6.Univ Manitoba, Dept Biol Sci, Winnipeg, MB, Canada
推荐引用方式 GB/T 7714	Yang, Ke,Wu, Jiandong,Santos, Susy,et al. Recent development of portable imaging platforms for cell-based assays[J]. BIOSENSORS & BIOELECTRONICS,2019,124:150-160.
APA	Yang, Ke,Wu, Jiandong,Santos, Susy,Liu, Yong,Zhu, Ling,&Lin, Francis.(2019).Recent development of portable imaging platforms for cell-based assays.BIOSENSORS & BIOELECTRONICS,124,150-160.
MLA	Yang, Ke,et al."Recent development of portable imaging platforms for cell-based assays".BIOSENSORS & BIOELECTRONICS 124(2019):150-160.