NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy | |
Nie, Rongrong1; Liu, Hongji2; Hu, Lin2; Gu, Xinyu3; Qian, Junchao4; Wang, Hui2 | |
刊名 | JOURNAL OF MATERIALS CHEMISTRY B |
2018-12-21 | |
卷号 | 6期号:47页码:7794-7799 |
ISSN号 | 2050-750X |
DOI | 10.1039/c8tb02398k |
通讯作者 | Wang, Hui(hw39@hmfl.ac.cn) |
英文摘要 | Herein, we present a light-switchable drug delivery system based on chitosan-gated carbon-based nanocarriers (CGC NCs) that exhibit a loading capacity for doxorubicin as high as similar to 89.65 wt% and controlled on/off release with/without NIR irradiation. In vitro and in vivo results show that the CGC NCs manifest high efficacy for cancer therapy through a synergistic effect of combined chemo-photothermal treatment. |
资助项目 | National Key Technologies RD Program[2016 YFA0401801] ; Chinese Academy of Sciences[1600000012] |
WOS关键词 | PHOTOTHERMAL THERAPY ; DELIVERY SYSTEMS ; IRON-OXIDE ; CHEMOTHERAPY ; NANOPARTICLES ; CARRIER ; COMBINATION ; NANOTECHNOLOGY ; NANOHYBRIDS ; BEHAVIOR |
WOS研究方向 | Materials Science |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000452319700002 |
资助机构 | National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences |
内容类型 | 期刊论文 |
源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/41066] |
专题 | 合肥物质科学研究院_中科院强磁场科学中心 |
通讯作者 | Wang, Hui |
作者单位 | 1.Nanjing Univ, Med Sch, Nanjing Stomatol Hosp, Nanjing 210008, Jiangsu, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Anhui Key Lab Condensed Matter Phys Extreme Condi, Hefei 230031, Anhui, Peoples R China 3.Univ Washington, Dept Biochem, Seattle, WA 98195 USA 4.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei Canc Hosp, Hefei 230031, Anhui, Peoples R China |
推荐引用方式 GB/T 7714 | Nie, Rongrong,Liu, Hongji,Hu, Lin,et al. NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy[J]. JOURNAL OF MATERIALS CHEMISTRY B,2018,6(47):7794-7799. |
APA | Nie, Rongrong,Liu, Hongji,Hu, Lin,Gu, Xinyu,Qian, Junchao,&Wang, Hui.(2018).NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy.JOURNAL OF MATERIALS CHEMISTRY B,6(47),7794-7799. |
MLA | Nie, Rongrong,et al."NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy".JOURNAL OF MATERIALS CHEMISTRY B 6.47(2018):7794-7799. |
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