Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles

doi:10.1016/j.scitotenv.2018.08.064

	Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles
	Yang, Yaning 3,5; Xu, Shengmin 1,3; Xu, Guangmin 1,3; Liu, Rui 2; Xu, An 1,3,5; Chen, Shaopeng 1,3; Wu, Lijun 1,3,4,5
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2019-01-10
卷号	647 页码:1088-1096
关键词	Silver nanoparticles Ionic strength Transformation Toxicity Caenorhabditis elegans
ISSN号	0048-9697
DOI	10.1016/j.scitotenv.2018.08.064
通讯作者	Xu, Shengmin(shmxu@mail.ustc.edu.cn) ; Wu, Lijun(ljw@ipp.ac.cn)
英文摘要	In the environment, silver nanoparticles (AgNPs) undergo a number of potential transformations, such as aggregation, dissolution, and redox reactions. However, the transformation in ionic strength condition, as well as their related toxicity was not quite clear, especially in the in vivo system. In the present study, we comprehensively evaluated three different characteristics (ddH(2)O, EPA water and K+ medium (KM)) mediated changes in the physical morphology of AgNPs and the alteration of the toxicity to Caenorhabditis elegans (C. elegans). Our results showed besides the changes of AgNPs behavior such as the transformation of morphological, with the transmission electron microscopy we found for the first time that smaller nanoparticles (<5 nm) appeared around the pristine AgNPs after incubation in EPA or KM for 5 days. Together with these changes, the toxicity of AgNPs to C. elegans changed significantly, showing that a higher ionic strength medium resulted in greater toxicity to C. elegans, as measured by germ cell apoptosis, brood size and lifespan. More importantly, our results indicated that the higher toxicity of AgNPs to C. elegans reproduction was probably related to the appearance of the smaller-size AgNPs in higher ionic strength media. These findings highlight that toxicity assessments for the release of nanomaterial to the environment need to be improved to assess environmental safety more accurately. (C) 2018 Elsevier B.V. All rights reserved.
资助项目	National Basic Research 973 Program[2014CB932002] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB14030502] ; Key Program of 13th five-year plan, CASHIPS[KP-2017-05] ; National Natural Science Foundation of China[201707144] ; National Natural Science Foundation of China[21607157] ; Anhui Provincial Natural Science Foundation[1808085QB49]
WOS关键词	NATURAL ORGANIC-MATTER ; ZEBRAFISH DANIO-RERIO ; CAENORHABDITIS-ELEGANS ; DAPHNIA-MAGNA ; SHAPE TRANSFORMATION ; MEDIA COMPOSITION ; DISSOLUTION ; STABILITY ; IMPACT ; SIZE
WOS研究方向	Environmental Sciences & Ecology
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000447090400110
资助机构	National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/39370]
专题	中国科学院合肥物质科学研究院
通讯作者	Xu, Shengmin; Wu, Lijun
作者单位	1.Key Lab Environm Toxicol & Pollut Control Technol, Hefei 230031, Anhui, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, POB 1138, Hefei 230031, Anhui, Peoples R China 4.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China 5.Univ Sci & Technol China, Dept Environm Sci & Optoelect Technol, Hefei 230026, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yaning,Xu, Shengmin,Xu, Guangmin,et al. Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2019,647:1088-1096.
APA	Yang, Yaning.,Xu, Shengmin.,Xu, Guangmin.,Liu, Rui.,Xu, An.,...&Wu, Lijun.(2019).Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles.SCIENCE OF THE TOTAL ENVIRONMENT,647,1088-1096.
MLA	Yang, Yaning,et al."Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles".SCIENCE OF THE TOTAL ENVIRONMENT 647(2019):1088-1096.