Preparation of magnetic molecularly imprinted polymers functionalized carbon nanotubes for highly selective removal of aristolochic acid

doi:10.1016/j.chroma.2019.06.043

	Preparation of magnetic molecularly imprinted polymers functionalized carbon nanotubes for highly selective removal of aristolochic acid
	Li, Fei 1; Gao, Jie 1; Li, XiaoXuan 1; Li, Yijun 1,2; He, Xiwen 1; Chen, Langxing 1,3; Zhang, Yukui 1,4
刊名	JOURNAL OF CHROMATOGRAPHY A
	2019-09-27
卷号	1602 页码:168-177
关键词	Aristolochic acid I Carbon nanotubes Sol-gel Magnetic separation Traditional Chinese medicine
ISSN号	0021-9673
DOI	10.1016/j.chroma.2019.06.043
通讯作者	Chen, Langxing(lxchen@nankai.edu.cn)
英文摘要	In this work, we presented the preparation of magnetic carbon nanotubes (MCNTs) functionalized with molecularly imprinted polymers (MIPs) for effective removal of aristolochic acid I (AAI) in traditional Chinese medicine (TCM). MCNTs@AAI-MIPs was obtained via a facile and environmental friendly sol-gel process. Firstly, MCNTs were synthesized by a solvothermal method. Then, the template molecules were self-assembled with the functional monomer phenyltrimethoxysilane (PTMOS) in the presence of ethanol and water. Finally, AAI-MIPs film was coated on the MCNTs to obtain product MCNTs@AAI-MIPs using tetraethyl-orthosilicate (TEOS) as cross-linker. The morphology and structure of prepared MIPs were characterized by Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), X-ray diffraction (XRD), nitrogen gas adsorption and vibrating sample magnetometer (VSM). The adsorption properties were demonstrated by kinetic, isothermal and selective adsorption experiments. The results showed that the imprinted nanocomposites exhibited fast separation rate (10 s), high adsorption capacity (18.54 mu g.mg(-1)), short kinetic equilibrium time (15 min), and good selectivity to template molecule with imprinting factor (IF) of 3.17. A regression equation (y=57294x-4734.1) with good linearity was obtained in the concentration range of 0.1-200 mu g.mg(-1) for AAI with a correlation coefficient (R-2) of 0.9998. The limit of detection (LOD, S/N=3) was 0.034 mu g.mg(-1). Moreover, high recoveries ranged from 80% to 110% (RSD=3.27%-8.16%) were received in spiked TCM samples. The results suggested that the proposed MCNTs@AAI-MIPs could efficiently and specifically capture AAI from an actual complex TCM samples. (C) 2019 Elsevier B.V. All rights reserved.
资助项目	National Natural Science Foundation of China[21475067] ; Fundamental Research Funds for the Central Universities
WOS关键词	SOLID-PHASE EXTRACTION ; HERBAL MEDICINES ; NANOPARTICLES ; NANOCOMPOSITE ; PERFORMANCE ; GEL ; SEPARATION
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000482514100020
资助机构	National Natural Science Foundation of China ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/173371]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Chen, Langxing
作者单位	1.Nankai Univ, Coll Chem, Tianjin Key Lab Biosensing & Mol Recognit, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China 2.Nankai Univ, Natl Demonstrat Ctr Expt Chem Educ, Tianjin 300071, Peoples R China 3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Li, Fei,Gao, Jie,Li, XiaoXuan,et al. Preparation of magnetic molecularly imprinted polymers functionalized carbon nanotubes for highly selective removal of aristolochic acid[J]. JOURNAL OF CHROMATOGRAPHY A,2019,1602:168-177.
APA	Li, Fei.,Gao, Jie.,Li, XiaoXuan.,Li, Yijun.,He, Xiwen.,...&Zhang, Yukui.(2019).Preparation of magnetic molecularly imprinted polymers functionalized carbon nanotubes for highly selective removal of aristolochic acid.JOURNAL OF CHROMATOGRAPHY A,1602,168-177.
MLA	Li, Fei,et al."Preparation of magnetic molecularly imprinted polymers functionalized carbon nanotubes for highly selective removal of aristolochic acid".JOURNAL OF CHROMATOGRAPHY A 1602(2019):168-177.