Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives

doi:10.1039/c8ob01933a

	Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives
	Chen, Zhongxiang 1,2; Fan, Hongjun 3; Yang, Shiwei 1,2; Bian, Guangling 1,2; Song, Ling 1,2
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2018-10-07
卷号	16 期号:37 页码:8311-8317
ISSN号	1477-0520
DOI	10.1039/c8ob01933a
通讯作者	Bian, Guangling(glb@fjirsm.ac.cn) ; Song, Ling(songling@fjirsm.ac.cn)
英文摘要	A simple strategy for configurational assignments of alpha-amino acids has been developed by comparison of the proton NMR chemical shift values of the alpha hydrogens of N-phthaloyl protected alphaamino acids in the presence of (R)-CSA 1 and (S)-CSA 1, respectively. Highly resolved NMR spectra can be obtained directly on the mixed solution of the chiral solvating agents with N-phthaloyl protected alphaamino acids in NMR tubes, giving well distinguishable proton signals without interference which dramatically improve the accuracy of assignment and hasten the assigning procedure. The strategy is widely applicable for varied natural and non-natural amino acids.
资助项目	Chinese Academy of Sciences[XDB20000000] ; DICP[DICP DMTO201404] ; Natural Science Foundation of Fujian Province, China[2018J01029] ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences
WOS关键词	NMR-SPECTROSCOPY ; SOLVATING AGENTS ; ENANTIOSELECTIVE RECOGNITION ; SHIFT-REAGENT ; HYDROXY ACIDS ; DISCRIMINATION ; ASSIGNMENT ; VERSATILE ; COMPLEXATION ; ENANTIOMERS
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000483966100013
资助机构	Chinese Academy of Sciences ; Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; DICP ; DICP ; Natural Science Foundation of Fujian Province, China ; Natural Science Foundation of Fujian Province, China ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences ; Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, the Fujian Institute of Research on the Structure of Matter, the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/173302]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Bian, Guangling; Song, Ling
作者单位	1.Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Coal Ethylene Glycol & Its Related Techno, Fuzhou 350002, Fujian, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Chen, Zhongxiang,Fan, Hongjun,Yang, Shiwei,et al. Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2018,16(37):8311-8317.
APA	Chen, Zhongxiang,Fan, Hongjun,Yang, Shiwei,Bian, Guangling,&Song, Ling.(2018).Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives.ORGANIC & BIOMOLECULAR CHEMISTRY,16(37),8311-8317.
MLA	Chen, Zhongxiang,et al."Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives".ORGANIC & BIOMOLECULAR CHEMISTRY 16.37(2018):8311-8317.