Recent advances in enrichment techniques for trace analysis in capillary electrophoresis

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Recent advances in enrichment techniques for trace analysis in capillary electrophoresis
	Wen, Yingying 1,2; Li, Jinhua1 ; Ma, Jiping 3; Chen, Lingxin1
刊名	ELECTROPHORESIS
	2012-10-01
卷号	33 期号:19-20 页码:2933-+
关键词	Capillary electrophoresis Microextraction On-line stacking Sample preparation Trace analysis
ISSN号	0173-0835
通讯作者	Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China.
产权排序	[Wen, Yingying; Li, Jinhua; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China; [Wen, Yingying] Univ Chinese Acad Sci, Beijing, Peoples R China; [Ma, Jiping] Qingdao Technol Univ, Inst Environm & Municipal Engn, Key Lab Environm Engn Shandong Prov, Qingdao, Peoples R China
中文摘要	CE is gaining great popularity as a well-established separation technique for many fields such as pharmaceutical research, clinical application, environmental monitoring, and food analysis, owing to its high resolving power, rapidity, and small amount of samples and reagents required. However, the sensitivity in CE analysis is still considered as being inferior to that in HPLC analysis. Diverse enrichment methods and techniques have been increasingly developed for overcoming this issue. In this review, we summarize the recent advances in enrichment techniques containing off-line preconcentration (sample preparation) and on-line concentration (sample stacking) to enhancing sensitivity in CE for trace analysis over the last 5 years. Some relatively new cleanup and preconcentration methods involving the use of dispersive liquidliquid microextraction, supercritical fluid extraction, matrix solid-phase dispersion, etc., and the continued use and improvement of conventional SPE, have been comprehensively reviewed and proved effective preconcentration alternatives for liquid, semisolid, and solid samples. As for CE on-line stacking, we give an overview of field amplication, sweeping, pH regulation, and transient isotachophoresis, and the coupling of multiple modes. Moreover, some limitations and comparisons related to such methods/techniques are also discussed. Finally, the combined use of various enrichment techniques and some significant attempts are proposed to further promote analytical merits in CE.
英文摘要	CE is gaining great popularity as a well-established separation technique for many fields such as pharmaceutical research, clinical application, environmental monitoring, and food analysis, owing to its high resolving power, rapidity, and small amount of samples and reagents required. However, the sensitivity in CE analysis is still considered as being inferior to that in HPLC analysis. Diverse enrichment methods and techniques have been increasingly developed for overcoming this issue. In this review, we summarize the recent advances in enrichment techniques containing off-line preconcentration (sample preparation) and on-line concentration (sample stacking) to enhancing sensitivity in CE for trace analysis over the last 5 years. Some relatively new cleanup and preconcentration methods involving the use of dispersive liquidliquid microextraction, supercritical fluid extraction, matrix solid-phase dispersion, etc., and the continued use and improvement of conventional SPE, have been comprehensively reviewed and proved effective preconcentration alternatives for liquid, semisolid, and solid samples. As for CE on-line stacking, we give an overview of field amplication, sweeping, pH regulation, and transient isotachophoresis, and the coupling of multiple modes. Moreover, some limitations and comparisons related to such methods/techniques are also discussed. Finally, the combined use of various enrichment techniques and some significant attempts are proposed to further promote analytical merits in CE.
学科主题	Biochemistry & Molecular Biology; Chemistry
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]	SOLID-PHASE EXTRACTION ; MICELLAR ELECTROKINETIC CHROMATOGRAPHY ; PRESSURIZED LIQUID EXTRACTION ; BAR SORPTIVE EXTRACTION ; SUPERCRITICAL-FLUID EXTRACTION ; SELECTIVE EXHAUSTIVE INJECTION ; MICROWAVE-ASSISTED EXTRACTION ; AMPLIFIED SAMPLE STACKING ; CLOUD POINT EXTRACTION ; DYNAMIC PH JUNCTION
收录类别	SCI
资助信息	National Natural Science Foundation of China [21105117, 21107057, 21275158]; Chinese Academy of Sciences [KZCX2-EW-206]; Natural Science Foundation of Shandong Province of China [ZR2010BQ027]; Yantai Research and Development Program of China [2010158]
原文出处	http://dx.doi.org/10.1002/elps.201200240
语种	英语
WOS记录号	WOS:000310289600001
公开日期	2013-03-08
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/6041]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Qingdao Technol Univ, Inst Environm & Municipal Engn, Key Lab Environm Engn Shandong Prov, Qingdao, Peoples R China
推荐引用方式 GB/T 7714	Wen, Yingying,Li, Jinhua,Ma, Jiping,et al. Recent advances in enrichment techniques for trace analysis in capillary electrophoresis[J]. ELECTROPHORESIS,2012,33(19-20):2933-+.
APA	Wen, Yingying,Li, Jinhua,Ma, Jiping,&Chen, Lingxin.(2012).Recent advances in enrichment techniques for trace analysis in capillary electrophoresis.ELECTROPHORESIS,33(19-20),2933-+.
MLA	Wen, Yingying,et al."Recent advances in enrichment techniques for trace analysis in capillary electrophoresis".ELECTROPHORESIS 33.19-20(2012):2933-+.