The functional divergence of two glgP homologues in Synechocystis sp PCC 6803

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	The functional divergence of two glgP homologues in Synechocystis sp PCC 6803
	Fu, J; Xu, XD
刊名	FEMS MICROBIOLOGY LETTERS
	2006-07-01
卷号	260 期号:2 页码:201-209
关键词	glgP functional divergence Synechocystis PCC 6803
ISSN号	0378-1097
通讯作者	Xu, XD, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China
中文摘要	Glycogen phosphorylase (GlgP, EC 2.4.1.1) catalyzes the cleavage of glycogen into glucose-1-phosphate (Glc-1-P), the first step in glycogen catabolism. Two glgP homologues are found in the genome of Synechocystis sp. PCC 6803, a unicellular cyanobacterium: sll1356 and slr1367. We report on the different functions of these glgP homologues. sll1356, rather than slr1367, is essential for growth at high temperatures. On the other hand, when CO2-fixation and the supply of glucose are both limited, slr1367 is the key factor in glycogen metabolism. In cells growing autotrophically, sll1356 plays a more important role in glycogen digestion than slr1367. This functional divergence is also supported by a phylogenetic analysis of glgP homologues in cyanobacteria.
英文摘要	Glycogen phosphorylase (GlgP, EC 2.4.1.1) catalyzes the cleavage of glycogen into glucose-1-phosphate (Glc-1-P), the first step in glycogen catabolism. Two glgP homologues are found in the genome of Synechocystis sp. PCC 6803, a unicellular cyanobacterium: sll1356 and slr1367. We report on the different functions of these glgP homologues. sll1356, rather than slr1367, is essential for growth at high temperatures. On the other hand, when CO2-fixation and the supply of glucose are both limited, slr1367 is the key factor in glycogen metabolism. In cells growing autotrophically, sll1356 plays a more important role in glycogen digestion than slr1367. This functional divergence is also supported by a phylogenetic analysis of glgP homologues in cyanobacteria.
学科主题	Microbiology
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Microbiology
研究领域[WOS]	Microbiology
关键词[WOS]	HEAT-SHOCK RESPONSE ; GLYCOGEN-PHOSPHORYLASE ; SEQUENCE ALIGNMENT ; HETEROTROPHIC GROWTH ; BACTERIAL GLYCOGEN ; MOLECULAR-CLONING ; ESCHERICHIA-COLI ; HISTIDINE KINASE ; HUMAN-LIVER ; GENE
收录类别	SCI
语种	英语
WOS记录号	WOS:000238579800011
公开日期	2010-10-13
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/152342/8938]
专题	水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文
作者单位	Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Fu, J,Xu, XD. The functional divergence of two glgP homologues in Synechocystis sp PCC 6803[J]. FEMS MICROBIOLOGY LETTERS,2006,260(2):201-209.
APA	Fu, J,&Xu, XD.(2006).The functional divergence of two glgP homologues in Synechocystis sp PCC 6803.FEMS MICROBIOLOGY LETTERS,260(2),201-209.
MLA	Fu, J,et al."The functional divergence of two glgP homologues in Synechocystis sp PCC 6803".FEMS MICROBIOLOGY LETTERS 260.2(2006):201-209.