Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin

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	Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin
	Zhu CS(祝纯生) ; Tang PP(汤平平) ; Yu B(俞飚)
刊名	J. Am. Chem. Soc.
	2008
卷号	130 期号:18 页码:5872-5873
ISSN号	0002-7863
其他题名	一个潜在的肿瘤药物:环状三萜皂甙Lobatoside E的全合成.
通讯作者	俞飚
英文摘要	Lobatoside E, a novel and complex cyclic triterpene saponin showing potent antitumor activities, has been synthesized for the first time, employing a highly modular approach. The synthesis, starting with oleanolic acid, D-glucose, D-galactose, L-arabinose, and L-rhamnose, requires a total of 73 steps, with the longest linear sequence of 31 steps and in 1.2% overall yield.
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ja801669r
语种	英语
WOS记录号	WOS:000255629400021
公开日期	2013-02-25
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/19085]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Zhu CS,Tang PP,Yu B. Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin[J]. J. Am. Chem. Soc.,2008,130(18):5872-5873.
APA	祝纯生,汤平平,&俞飚.(2008).Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin.J. Am. Chem. Soc.,130(18),5872-5873.
MLA	祝纯生,et al."Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin".J. Am. Chem. Soc. 130.18(2008):5872-5873.