SYNTHESIS AND DNA INTERACTION OF A Sm(III) COMPLEX OF A SCHIFF BASE DERIVED FROM VANILLIN AND L-TRYPTOPHAN

	SYNTHESIS AND DNA INTERACTION OF A Sm(III) COMPLEX OF A SCHIFF BASE DERIVED FROM VANILLIN AND L-TRYPTOPHAN
	Wang, Xing-ming ; Zhang, Yan ; Zhao, Ting-ting ; Ding, Li-sheng
刊名	BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA
	2011
卷号	25 期号:2 页码:197-207
关键词	Vanillin L-Tryptophan Sm(III) complex of Schiff base Herring sperm DNA Interaction
ISSN号	1011-3924
通讯作者	Wang, XM (reprint author), SW Univ Sci & Technol, Dept Chem, Sch Mat Sci & Engn, Mianyang 621010, Peoples R China.
产权排序	2
英文摘要	The interaction between the Sm(III) complex of an ionic Schiff base [HL](-), derived from vanillin and L-tryptophan, and herring sperm DNA at physiological pH (7.40) has been studied by UV-Vis absorption, fluorescence and viscosity methods. The binding ratios nSm(III) : nK[HL] = 1: 1 and nSm(III) L : nDNA = 5: 1 were confirmed by a mole ratio method. The calculated binding constants of [Sm(III)L](+) with DNA at 25 and 37 C were 1.19 x 10(5) M-1 and 3.96 x 10(4) M-1, respectively. The thermodynamic parameters demonstrate that the interaction between [Sm(III) L](+) and DNA is driven mainly by enthalpy. Fluorimetric studies show that [Sm(III) L](+) is able to displace intercalated acridine orange. Combined with Scatchard methods, circular dichroism spectroscopy and viscosity measurements, the results indicate that the interaction between [Sm(III) L](+) and herring sperm DNA is mainly by intercalation with some groove binding.
学科主题	Chemistry
收录类别	SCI
资助信息	National Natural Science Foundation of China[30572254]
语种	英语
WOS记录号	WOS:000303328500005
公开日期	2012-11-09
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23571]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Wang, Xing-ming,Zhang, Yan,Zhao, Ting-ting,et al. SYNTHESIS AND DNA INTERACTION OF A Sm(III) COMPLEX OF A SCHIFF BASE DERIVED FROM VANILLIN AND L-TRYPTOPHAN[J]. BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA,2011,25(2):197-207.
APA	Wang, Xing-ming,Zhang, Yan,Zhao, Ting-ting,&Ding, Li-sheng.(2011).SYNTHESIS AND DNA INTERACTION OF A Sm(III) COMPLEX OF A SCHIFF BASE DERIVED FROM VANILLIN AND L-TRYPTOPHAN.BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA,25(2),197-207.
MLA	Wang, Xing-ming,et al."SYNTHESIS AND DNA INTERACTION OF A Sm(III) COMPLEX OF A SCHIFF BASE DERIVED FROM VANILLIN AND L-TRYPTOPHAN".BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA 25.2(2011):197-207.