Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 固体润滑国家重点实验室

	Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery
	Wang TM(王廷梅)
刊名	Colloids and Surfaces A: Physicochem. Eng. Aspects
	2011
卷号	375 页码:163-168
关键词	Superparamagnetic nanoparticle Block copolymer Environmental responsive Surface-initiated atom transfer radical polymerization Drug delivery
ISSN号	0927-7757
通讯作者	刘鹏
中文摘要	The functional block copolymer (poly(hydroyethyl acrylate-b-N-isopropylacrylamide), P(HEA-b- NIPAm)) grafted Fe3O4 nanoparticles (Fe3O4@P(HEA-b-NIPAm)) with temperature-responsive poly(N- isopropylacrylamide) (PNIPAm) as the skin layer were designed via the consecutive surface-initiated atom transfer radical polymerization (SI-ATRP) from the surfaces of the superparamagnetic Fe3O4 nanoparticles. The targeted functional and temperature-sensitive nanoparticles were characterized by the FT-IR, XPS, TEM, VSM, andDLS techniques. It is expected that themulti-functional nanoparticles could be used for the targeted and controlled drug delivery.
学科主题	材料科学与物理化学
收录类别	SCI
资助信息	the National Nature Science Foundation of China(Grant NO.20904017);Program for New Century Excellent Talents in University (Grant NO.NCET-09-0441);the National Science Foundation for Fostering Talents in Basic Research of the National Natural Science Foundation of China (Grant NO.J0730425)
语种	英语
WOS记录号	WOS:000287285500023
公开日期	2012-09-24
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/700]
专题	兰州化学物理研究所_固体润滑国家重点实验室兰州化学物理研究所_先进润滑与防护材料研究发展中心
推荐引用方式 GB/T 7714	Wang TM. Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery[J]. Colloids and Surfaces A: Physicochem. Eng. Aspects,2011,375:163-168.
APA	王廷梅.(2011).Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery.Colloids and Surfaces A: Physicochem. Eng. Aspects,375,163-168.
MLA	王廷梅."Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery".Colloids and Surfaces A: Physicochem. Eng. Aspects 375(2011):163-168.