Iron-catalyzed Michael reactions revisited: a synthetically useful process for the preparation of tri-carbonyl compounds and chiral warfarin

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	Iron-catalyzed Michael reactions revisited: a synthetically useful process for the preparation of tri-carbonyl compounds and chiral warfarin
	Xia CG(夏春谷)
刊名	Tetrahedron Lett.
	2010
卷号	51 页码:3836-3839
关键词	Iron catalysis Michael reaction Warfarin Asymmetric catalysis Primary amine
ISSN号	0040-4039
通讯作者	徐利文
中文摘要	The LBAs (Lewis acid-assisted Brønsted acid catalysis) is proposed as possible mechanistic process in the simple FeCl3-catalyzed Michael reactions of chalcones with active methylene compounds in organic solvents. And iron salts were found to be effective promoters in the asymmetric Michael addition of 4-hydroxycoumarin to a,b-unsaturated ketone, which resulted in excellent yield and high level of enantioselectivity (up to 91% ee) in the presence of low catalytic amount of iron and simple chiral primary amine.
学科主题	物理化学
收录类别	SCI
资助信息	the National Natural Science Founder of China (No. 20973051);Zhejiang Provincial Natural Science Foundation of China (Y4090139)
语种	英语
WOS记录号	WOS:000279864100035
公开日期	2012-09-21
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/497]
专题	兰州化学物理研究所_OSSO国家重点实验室
推荐引用方式 GB/T 7714	Xia CG. Iron-catalyzed Michael reactions revisited: a synthetically useful process for the preparation of tri-carbonyl compounds and chiral warfarin[J]. Tetrahedron Lett.,2010,51:3836-3839.
APA	夏春谷.(2010).Iron-catalyzed Michael reactions revisited: a synthetically useful process for the preparation of tri-carbonyl compounds and chiral warfarin.Tetrahedron Lett.,51,3836-3839.
MLA	夏春谷."Iron-catalyzed Michael reactions revisited: a synthetically useful process for the preparation of tri-carbonyl compounds and chiral warfarin".Tetrahedron Lett. 51(2010):3836-3839.